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Lara Mangravite

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Papers

Gershon RC, Sliwinski MJ, Mangravite L, King JW, Kaat AJ, Weiner MW, Rentz DM. (2022). The Mobile Toolbox for monitoring cognitive function. The Lancet. Neurology, 21(7)

Heath L, Earls JC, Magis AT, Kornilov SA, Lovejoy JC, Funk CC, Rappaport N, Logsdon BA, Mangravite LM, Kunkle BW, Martin ER, Naj AC, Ertekin-Taner N, Golde TE, Hood L, Price ND, . (2022). Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90. Scientific reports, 12(1)

Kotredes KP, Oblak A, Pandey RS, Lin PB, Garceau D, Williams H, Uyar A, O'Rourke R, O'Rourke S, Ingraham C, Bednarczyk D, Belanger M, Cope Z, Foley KE, Logsdon BA, Mangravite LM, Sukoff Rizzo SJ, Territo PR, Carter GW, Sasner M, Lamb BT, Howell GR. (2022). R47H. Frontiers in aging neuroscience, (14)

Chaibub Neto E, Perumal TM, Pratap A, Tediarjo A, Bot BM, Mangravite L, Omberg L. (2022). Disentangling personalized treatment effects from "time-of-the-day" confounding in mobile health studies. PloS one, 17(8)

Oblak AL, Lin PB, Kotredes KP, Pandey RS, Garceau D, Williams HM, Uyar A, O'Rourke R, O'Rourke S, Ingraham C, Bednarczyk D, Belanger M, Cope ZA, Little GJ, Williams SG, Ash C, Bleckert A, Ragan T, Logsdon BA, Mangravite LM, Sukoff Rizzo SJ, Territo PR, Carter GW, Howell GR, Sasner M, Lamb BT. (2021). Comprehensive Evaluation of the 5XFAD Mouse Model for Preclinical Testing Applications: A MODEL-AD Study. Frontiers in aging neuroscience, (13)

Sieberts SK, Schaff J, Duda M, Pataki BÁ, Sun M, Snyder P, Daneault JF, Parisi F, Costante G, Rubin U, Banda P, Chae Y, Chaibub Neto E, Dorsey ER, Aydın Z, Chen A, Elo LL, Espino C, Glaab E, Goan E, Golabchi FN, Görmez Y, Jaakkola MK, Jonnagaddala J, Klén R, Li D, McDaniel C, Perrin D, Perumal TM, Rad NM, Rainaldi E, Sapienza S, Schwab P, Shokhirev N, Venäläinen MS, Vergara-Diaz G, Zhang Y, , Wang Y, Guan Y, Brunner D, Bonato P, Mangravite LM, Omberg L. (2021). Crowdsourcing digital health measures to predict Parkinson's disease severity: the Parkinson's Disease Digital Biomarker DREAM Challenge. NPJ digital medicine, 4(1)

Kotredes KP, Oblak A, Pandey RS, Lin PB, Garceau D, Williams H, Uyar A, O'Rourke R, O'Rourke S, Ingraham C, Bednarycek D, Belanger M, Cope Z, Foley KE, Logsdon BA, Mangravite LM, Sukoff Rizzo SJ, Territo PR, Carter GW, Sasner M, Lamb BT, Howell GR. (2021). Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H. Frontiers in aging neuroscience, (13)

Mangravite L, Mooney SD, Friedberg I, Guinney J. Establishing the reliability of algorithms. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, (26)

Omberg L, Chaibub Neto E, Perumal TM, Pratap A, Tediarjo A, Adams J, Bloem BR, Bot BM, Elson M, Goldman SM, Kellen MR, Kieburtz K, Klein A, Little MA, Schneider R, Suver C, Tarolli C, Tanner CM, Trister AD, Wilbanks J, Dorsey ER, Mangravite LM. (2021). Remote smartphone monitoring of Parkinson's disease and individual response to therapy. Nature biotechnology

Baird DA, Liu JZ, Zheng J, Sieberts SK, Perumal T, Elsworth B, Richardson TG, Chen CY, Carrasquillo MM, Allen M, Reddy JS, De Jager PL, Ertekin-Taner N, Mangravite LM, Logsdon B, Estrada K, Haycock PC, Hemani G, Runz H, Smith GD, Gaunt TR, . (2021). Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome. PLoS genetics, 17(1)

Webster DE, Tummalacherla M, Higgins M, Wing D, Ashley E, Kelly VE, McConnell MV, Muse ED, Olgin JE, Mangravite LM, Godino J, Kellen MR, Omberg L. (2021). Smartphone-Based VO2max Measurement With Heart Snapshot in Clinical and Real-world Settings With a Diverse Population: Validation Study. JMIR mHealth and uHealth, 9(6)

Gockley J, Montgomery KS, Poehlman WL, Wiley JC, Liu Y, Gerasimov E, Greenwood AK, Sieberts SK, Wingo AP, Wingo TS, Mangravite LM, Logsdon BA. (2021). Multi-tissue neocortical transcriptome-wide association study implicates 8 genes across 6 genomic loci in Alzheimer's disease. Genome medicine, 13(1)

Pratap A, Grant D, Vegesna A, Tummalacherla M, Cohan S, Deshpande C, Mangravite L, Omberg L. (2020). Evaluating the Utility of Smartphone-Based Sensor Assessments in Persons With Multiple Sclerosis in the Real-World Using an App (elevateMS): Observational, Prospective Pilot Digital Health Study. JMIR mHealth and uHealth, 8(10)

Oblak AL, Forner S, Territo PR, Sasner M, Carter GW, Howell GR, Sukoff-Rizzo SJ, Logsdon BA, Mangravite LM, Mortazavi A, Baglietto-Vargas D, Green KN, MacGregor GR, Wood MA, Tenner AJ, LaFerla FM, Lamb BT, , . (2020). Model organism development and evaluation for late-onset Alzheimer's disease: MODEL-AD. Alzheimer's & dementia (New York, N. Y.), 6(1)

Greenwood AK, Montgomery KS, Kauer N, Woo KH, Leanza ZJ, Poehlman WL, Gockley J, Sieberts SK, Bradic L, Logsdon BA, Peters MA, Omberg L, Mangravite LM. (2020). The AD Knowledge Portal: A Repository for Multi-Omic Data on Alzheimer's Disease and Aging. Current protocols in human genetics, 108(1)

Schneider RB, Omberg L, Macklin EA, Daeschler M, Bataille L, Anthwal S, Myers TL, Baloga E, Duquette S, Snyder P, Amodeo K, Tarolli CG, Adams JL, Callahan KF, Gottesman J, Kopil CM, Lungu C, Ascherio A, Beck JC, Biglan K, Espay AJ, Tanner C, Oakes D, Shoulson I, Novak D, Kayson E, Ray Dorsey E, Mangravite L, Schwarzschild MA, Simuni T, . (2020). Design of a virtual longitudinal observational study in Parkinson's disease (AT-HOME PD). Annals of clinical and translational neurology

Pratap A, Neto EC, Snyder P, Stepnowsky C, Elhadad N, Grant D, Mohebbi MH, Mooney S, Suver C, Wilbanks J, Mangravite L, Heagerty PJ, Areán P, Omberg L. (2020). Indicators of retention in remote digital health studies: a cross-study evaluation of 100,000 participants. NPJ digital medicine, 3(1)

Suver CM, Hamann JK, Chin EM, Goldstein FC, Blazel HM, Manzanares CM, Doerr MJ, Asthana SJ, Mangravite LM, Levey AI, Lah JJ, Edwards DF. (2020). Informed Consent in Two Alzheimer's Disease Research Centers: Insights From Research Coordinators. AJOB empirical bioethics, 11(2)

Wan YW, Al-Ouran R, Mangleburg CG, Perumal TM, Lee TV, Allison K, Swarup V, Funk CC, Gaiteri C, Allen M, Wang M, Neuner SM, Kaczorowski CC, Philip VM, Howell GR, Martini-Stoica H, Zheng H, Mei H, Zhong X, Kim JW, Dawson VL, Dawson TM, Pao PC, Tsai LH, Haure-Mirande JV, Ehrlich ME, Chakrabarty P, Levites Y, Wang X, Dammer EB, Srivastava G, Mukherjee S, Sieberts SK, Omberg L, Dang KD, Eddy JA, Snyder P, Chae Y, Amberkar S, Wei W, Hide W, Preuss C, Ergun A, Ebert PJ, Airey DC, Mostafavi S, Yu L, Klein HU, , Carter GW, Collier DA, Golde TE, Levey AI, Bennett DA, Estrada K, Townsend TM, Zhang B, Schadt E, De Jager PL, Price ND, Ertekin-Taner N, Liu Z, Shulman JM, Mangravite LM, Logsdon BA. (2020). Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell reports, 32(2)

Mukherjee S, Heath L, Preuss C, Jayadev S, Garden GA, Greenwood AK, Sieberts SK, De Jager PL, Ertekin-Taner N, Carter GW, Mangravite LM, Logsdon BA. (2020). Molecular estimation of neurodegeneration pseudotime in older brains. Nature communications, 11(1)

Sieberts SK, Perumal TM, Carrasquillo MM, Allen M, Reddy JS, Hoffman GE, Dang KK, Calley J, Ebert PJ, Eddy J, Wang X, Greenwood AK, Mostafavi S, , , Omberg L, Peters MA, Logsdon BA, De Jager PL, Ertekin-Taner N, Mangravite LM. (2020). Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions. Scientific data, 7(1)

Preuss C, Pandey R, Piazza E, Fine A, Uyar A, Perumal T, Garceau D, Kotredes KP, Williams H, Mangravite LM, Lamb BT, Oblak AL, Howell GR, Sasner M, Logsdon BA, , Carter GW. (2020). A novel systems biology approach to evaluate mouse models of late-onset Alzheimer's disease. Molecular neurodegeneration, 15(1)

Omberg L, Chaibub Neto E, Mangravite LM. (2020). Data Science Approaches for Effective Use of Mobile Device-Based Collection of Real-World Data. Clinical pharmacology and therapeutics

Mukherjee S, Heath L, Preuss C, Jayadev S, Garden GA, Greenwood AK, Sieberts SK, De Jager PL, Ertekin-Taner N, Carter GW, Mangravite LM, Logsdon BA. (2020). Author Correction: Molecular estimation of neurodegeneration pseudotime in older brains. Nature communications, 11(1)

Gold ER, Ali-Khan SE, Allen L, Ballell L, Barral-Netto M, Carr D, Chalaud D, Chaplin S, Clancy MS, Clarke P, Cook-Deegan R, Dinsmore AP, Doerr M, Federer L, Hill SA, Jacobs N, Jean A, Jefferson OA, Jones C, Kahl LJ, Kariuki TM, Kassel SN, Kiley R, Kittrie ER, Kramer B, Lee WH, MacDonald E, Mangravite LM, Marincola E, Mietchen D, Molloy JC, Namchuk M, Nosek BA, Paquet S, Pirmez C, Seyller A, Skingle M, Spadotto SN, Staniszewska S, Thelwall M. (2019). An open toolkit for tracking open science partnership implementation and impact. Gates open research, (3)

Kueffner R, Zach N, Bronfeld M, Norel R, Atassi N, Balagurusamy V, Di Camillo B, Chio A, Cudkowicz M, Dillenberger D, Garcia-Garcia J, Hardiman O, Hoff B, Knight J, Leitner ML, Li G, Mangravite L, Norman T, Wang L, , Xiao J, Fang WC, Peng J, Yang C, Chang HJ, Stolovitzky G. (2019). Stratification of amyotrophic lateral sclerosis patients: a crowdsourcing approach. Scientific reports, 9(1)

Mukherjee S, Perumal TM, Daily K, Sieberts SK, Omberg L, Preuss C, Carter GW, Mangravite LM, Logsdon BA. (2019). Identifying and ranking potential driver genes of Alzheimer's disease using multiview evidence aggregation. Bioinformatics (Oxford, England), 35(14)

Allaway RJ, La Rosa S, Verma S, Mangravite L, Guinney J, Blakeley J, Bakker A, Gosline SJC. (2019). Engaging a community to enable disease-centric data sharing with the NF Data Portal. Scientific data, 6(1)

Fourati S, Talla A, Mahmoudian M, Burkhart JG, Klén R, Henao R, Yu T, Aydın Z, Yeung KY, Ahsen ME, Almugbel R, Jahandideh S, Liang X, Nordling TEM, Shiga M, Stanescu A, Vogel R, , Pandey G, Chiu C, McClain MT, Woods CW, Ginsburg GS, Elo LL, Tsalik EL, Mangravite LM, Sieberts SK. (2018). A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection. Nature communications, 9(1)

Wang M, Beckmann ND, Roussos P, Wang E, Zhou X, Wang Q, Ming C, Neff R, Ma W, Fullard JF, Hauberg ME, Bendl J, Peters MA, Logsdon B, Wang P, Mahajan M, Mangravite LM, Dammer EB, Duong DM, Lah JJ, Seyfried NT, Levey AI, Buxbaum JD, Ehrlich M, Gandy S, Katsel P, Haroutunian V, Schadt E, Zhang B. (2018). The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease. Scientific data, (5)

De Jager PL, Ma Y, McCabe C, Xu J, Vardarajan BN, Felsky D, Klein HU, White CC, Peters MA, Lodgson B, Nejad P, Tang A, Mangravite LM, Yu L, Gaiteri C, Mostafavi S, Schneider JA, Bennett DA. (2018). A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research. Scientific data, (5)

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