MIDAS Latin America Seminar: Risk of Rabies from Animal Exposures in the US and Implications for Post-exposure Prophylaxis Administration

Thursday, October 20th


Thursday, October 20th


Please join us for the next MIDAS Latin America Seminar. 

Date: Thursday October 20, 2022 12:00 pm Eastern Daylight Time (US) 

*We are currently observing Daylight Saving Time in the Eastern Time Zone.
Be sure that you account for differences depending on your local time zone.*

(11:00am – 12:00pm *Bogota*, 1:00pm – 2:00pm *Rio*, 12:00pm – 1:00pm *San Juan*)

Speaker: Dr. Kelly Charniga from the CDC’s National Center for Emerging and Zoonotic Infectious Diseases

Topic: “Risk of Rabies from Animal Exposures in the US and Implications for Post-exposure Prophylaxis Administration.”

Importance. In the US, rabies post-exposure prophylaxis (PEP) is expensive and often used inappropriately. Existing guidelines for PEP administration are qualitative, updated infrequently, and do not capture uncertainty. Objective. To estimate the risk of rabies virus (RABV) infection in humans from animal exposures in the US. Main outcome. A quantitative and standardized approach for assisting healthcare providers and public health professionals in determining the appropriateness of initiating PEP. Results. Exposures involving raccoons, skunks, and foxes that were unprovoked and ill or acting strangely had the highest probability of the animal testing positive for RABV, although the risk varied by location of exposure within the US.

Titulo: El riesgo de rabia debido a exposición con animales en EEUU y sus implicaciones para el uso de la profilaxis posexposición.

Importancia. En EEUU, la profilaxis posexposición (PEP) es costosa y se usa frecuentemente de manera inapropiada. Las guías actuales de PEP son cualitativas, se actualizan raramente, y no representan adecuadamente la incertidumbre. Objetivo. Estimar el riesgo de infección en humanos por el virus de la rabia (RABV) debido a exposición con animales.  Resultados principales. Un método cuantitativo estandarizado para asistir proveedores y profesionales de salud pública para determinar el uso apropiado de PEP. Resultados. Tipos de exposición que involucraron zorrillos, mapaches, y zorros, que no fueron provocados y estaban enfermos, o actuando de manera extraña, obtuvieron la mayor probabilidad de un resultado positivo de RABV, aunque el riesgo fue variado dependiendo de la ubicación.



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