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MIDAS Webinar: An infectious disease journey, through the lens of transmission

The MIDAS Webinar Series features research by MIDAS members, and is open to the public. 

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Date: Friday, October 29th
Time: 12:00pm – 1:00pm Eastern (USA)

Topic: An infectious disease journey, through the lens of transmission

Speaker: Dr. Madikay Senghore

Abstract: Madikay is passionate about the evolution of bacterial pathogens and is keen to understand the drivers of transmission. In this talk he will highlight how gaps in sampling can hinder genomic inferences into transmission, and share some examples of methods implemented to overcome these challenges. The talk will showcase unique genomics datasets from West Africa to demonstrate how genomics can be leveraged to understand the evolution and transmission of bacterial pathogens in a high burden, endemic setting. To round off the talk, he will introduce recent work on an experimental mouse transmission model, which uses deep sequencing to retrace transmission steps: a step towards high precision contact tracing and epidemic control.

Bio: Dr. Senghore is a Postdoctoral Research Fellow in the Center for Communicable Disease Dynamics at Harvard University. He studies the genomic epidemiology of pathogens to understand the impact of clinical interventions like vaccination and antimicrobial therapy on the population structure of pathogens such as Streptococcus pneumoniae, Staphylococcus aureus and Mycobacterium tuberculosis. Dr. Senghore has developed a keen interest in understanding the determinants that shape the transmission dynamics of bacterial infections, including the role of bottleneck sizes and within host evolution, as well as other factors such as spatial and temporal distance between hosts.