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Using a novel resource to decrease proteomic biomarker identification time.

Abstract

The Empirical Proteomic Ontology Knowledge Base (EPO-KB) is an online database that represents current knowledge of biomarkers and contains associations between mass-to-charge (m/z) ratios of mass-spectrometry peaks to proteins. Such a database is a useful tool for identifying putative proteins associated with a m/z ratio. At present, EPO-KB contains data that have been extracted from 120 published research papers. It has been used in successful identification of a protein associated with a biomarker.

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Citation:

Lustgarten JL, Visweswaran S, Grover H, Kimmel CP, Ryberg H, Bowser RP, Gopalakrishnan V, Hogan WR. (2008). Using a novel resource to decrease proteomic biomarker identification time. AMIA ... Annual Symposium proceedings. AMIA Symposium