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Caroline Buckee

Associate Professor

Education

Affiliations

Projects

MIDAS CENTER FOR COMMUNICABLE DISEASE DYNAMICS

National Institutes of Health, National Institute of General Medical Sciences
People: Laura White, Ted Cohen, William Hanage, Rene Niehus, Ben Cowling, Tyler Brown, Joseph Wu, Mauricio Santillana Guzman, Joseph Lewnard, Aimee Taylor, Pablo Martinez de Salazar, Lerato Magosi, Edward Goldstein, Christine Tedijanto, Tigist Menkir, Sze Man Leung, Hsiao-Han Chang, Caroline Buckee, Pamela Martinez, Marc Lipsitch
2009 – 2020

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Papers

De Salazar PM, Niehus R, Taylor A, Buckee CO, Lipsitch M. (2020). Identifying Locations with Possible Undetected Imported Severe Acute Respiratory Syndrome Coronavirus 2 Cases by Using Importation Predictions. Emerging infectious diseases, 26(7)

Buckee CO, Balsari S, Chan J, Crosas M, Dominici F, Gasser U, Grad YH, Grenfell B, Halloran ME, Kraemer MUG, Lipsitch M, Metcalf CJE, Meyers LA, Perkins TA, Santillana M, Scarpino SV, Viboud C, Wesolowski A, Schroeder A. (2020). Aggregated mobility data could help fight COVID-19. Science (New York, N.Y.)

Peak CM, Kahn R, Grad YH, Childs LM, Li R, Lipsitch M, Buckee CO. (2020). Individual quarantine versus active monitoring of contacts for the mitigation of COVID-19: a modelling study. The Lancet. Infectious diseases

Obeng-Adjei N, Larremore DB, Turner L, Ongoiba A, Li S, Doumbo S, Yazew TB, Kayentao K, Miller LH, Traore B, Pierce SK, Buckee CO, Lavstsen T, Crompton PD, Tran TM. (2020). Longitudinal analysis of naturally acquired PfEMP1 CIDR domain variant antibodies identifies associations with malaria protection. JCI insight

Holmdahl I, Buckee C. (2020). Wrong but Useful - What Covid-19 Epidemiologic Models Can and Cannot Tell Us. The New England journal of medicine

Kahn R, Peak CM, Fernández-Gracia J, Hill A, Jambai A, Ganda L, Castro MC, Buckee CO. (2020). Incubation periods impact the spatial predictability of cholera and Ebola outbreaks in Sierra Leone. Proceedings of the National Academy of Sciences of the United States of America

Chin T, Buckee CO, Mahmud AS. (2020). Quantifying the success of measles vaccination campaigns in the Rohingya refugee camps. Epidemics, (30)

Sinha I, Sayeed AA, Uddin D, Wesolowski A, Zaman SI, Faiz MA, Ghose A, Rahman MR, Islam A, Karim MJ, Saha A, Rezwan MK, Shamsuzzaman AKM, Jhora ST, Aktaruzzaman MM, Chang HH, Miotto O, Kwiatkowski D, Dondorp AM, Day NPJ, Hossain MA, Buckee C, Maude RJ. (2020). Mapping the travel patterns of people with malaria in Bangladesh. BMC medicine, 18(1)

De Salazar Pablo M, Niehus Rene, Taylor Aimee, Buckee Caroline O, Lipsitch Marc. (2020). Using predicted imports of 2019-nCoV cases to determine locations that may not be identifying all imported cases

Peak Corey M, Kahn Rebecca, Grad Yonatan H, Childs Lauren M, Li Ruoran, Lipsitch Marc, Buckee Caroline O. (2020). Modeling the Comparative Impact of Individual Quarantine vs. Active Monitoring of Contacts for the Mitigation of COVID-19. Cold Spring Harbor Laboratory Press

Cai FY, DeSimone TM, Hansen E, Jennings CV, Bei AK, Ahouidi AD, Mboup S, Duraisingh MT, Buckee CO. (2020). Accounting for red blood cell accessibility reveals distinct invasion strategies in Plasmodium falciparum strains. PLoS computational biology, 16(4)

Martinez PP, Mahmud AS, Yunus M, Faruque ASG, Ahmed T, Pascual M, Buckee CO. (2020). Tube Well Use as Protection Against Rotavirus Infection During the Monsoons in an Urban Setting. The Journal of infectious diseases, 221(2)

Taylor AR, Jacob PE, Neafsey DE, Buckee CO. (2019). Estimating Relatedness Between Malaria Parasites. Genetics, 212(4)

Kahn R, Mahmud AS, Schroeder A, Aguilar Ramirez LH, Crowley J, Chan J, Buckee CO. (2019). Rapid Forecasting of Cholera Risk in Mozambique: Translational Challenges and Opportunities. Prehospital and disaster medicine, 34(5)

Chang HH, Wesolowski A, Sinha I, Jacob CG, Mahmud A, Uddin D, Zaman SI, Hossain MA, Faiz MA, Ghose A, Sayeed AA, Rahman MR, Islam A, Karim MJ, Rezwan MK, Shamsuzzaman AKM, Jhora ST, Aktaruzzaman MM, Drury E, Gonçalves S, Kekre M, Dhorda M, Vongpromek R, Miotto O, Engø-Monsen K, Kwiatkowski D, Maude RJ, Buckee C. (2019). Mapping imported malaria in Bangladesh using parasite genetic and human mobility data. Elife, (8)

Paton DG, Childs LM, Itoe MA, Holmdahl IE, Buckee CO, Catteruccia F. (2019). Exposing Anopheles mosquitoes to antimalarials blocks Plasmodium parasite transmission. Nature, 567(7747)

Recker M, Bull PC, Buckee CO. (2018). Recent advances in the molecular epidemiology of clinical malaria. F1000Research, (7)

Kishore N, Marqués D, Mahmud A, Kiang MV, Rodriguez I, Fuller A, Ebner P, Sorensen C, Racy F, Lemery J, Maas L, Leaning J, Irizarry RA, Balsari S, Buckee CO. (2018). Mortality in Puerto Rico after Hurricane Maria. The New England journal of medicine, 379(2)

Peak CM, Wesolowski A, Zu Erbach-Schoenberg E, Tatem AJ, Wetter E, Lu X, Power D, Weidman-Grunewald E, Ramos S, Moritz S, Buckee CO, Bengtsson L. (2018). Population mobility reductions associated with travel restrictions during the Ebola epidemic in Sierra Leone: use of mobile phone data. International journal of epidemiology, 47(5)

Georgieva M, Buckee CO, Lipsitch M. (2019). Models of immune selection for multi-locus antigenic diversity of pathogens. Nature reviews. Immunology, 19(1)

Wesolowski A, Taylor AR, Chang HH, Verity R, Tessema S, Bailey JA, Alex Perkins T, Neafsey DE, Greenhouse B, Buckee CO. (2018). Correction to: Mapping malaria by combining parasite genomic and epidemiologic data. BMC medicine, 16(1)

Lam HM, Wesolowski A, Hung NT, Nguyen TD, Nhat NTD, Todd S, Vinh DN, Vy NHT, Thao TTN, Thanh NTL, Tin PT, Minh NNQ, Bryant JE, Buckee CO, Ngoc TV, Chau NVV, Thwaites GE, Farrar J, Tam DTH, Vinh H, Boni MF. (2018). Nonannual seasonality of influenza-like illness in a tropical urban setting. Influenza and other respiratory viruses, 12(6)

Ihantamalala FA, Herbreteau V, Rakotoarimanana FMJ, Rakotondramanga JM, Cauchemez S, Rahoilijaona B, Pennober G, Buckee CO, Rogier C, Metcalf CJE, Wesolowski A. (2018). Estimating sources and sinks of malaria parasites in Madagascar. Nature communications, 9(1)

Buckee CO, Cardenas MIE, Corpuz J, Ghosh A, Haque F, Karim J, Mahmud AS, Maude RJ, Mensah K, Motaze NV, Nabaggala M, Metcalf CJE, Mioramalala SA, Mubiru F, Peak CM, Pramanik S, Rakotondramanga JM, Remera E, Sinha I, Sovannaroth S, Tatem AJ, Zaw W. (2018). Productive disruption: opportunities and challenges for innovation in infectious disease surveillance. BMJ global health, 3(1)

Wesolowski A, Taylor AR, Chang HH, Verity R, Tessema S, Bailey JA, Alex Perkins T, Neafsey DE, Greenhouse B, Buckee CO. (2018). Mapping malaria by combining parasite genomic and epidemiologic data. BMC medicine, 16(1)

Wesolowski A, Winter A, Tatem AJ, Qureshi T, Engø-Monsen K, Buckee CO, Cummings DAT, Metcalf CJE. (2018). Measles outbreak risk in Pakistan: exploring the potential of combining vaccination coverage and incidence data with novel data-streams to strengthen control. Epidemiology and infection, 146(12)

Peak CM, Reilly AL, Azman AS, Buckee CO. (2018). Prolonging herd immunity to cholera via vaccination: Accounting for human mobility and waning vaccine effects. PLoS neglected tropical diseases, 12(2)

Peak CM, Childs LM, Grad YH, Buckee CO. (2017). Comparing nonpharmaceutical interventions for containing emerging epidemics. Proceedings of the National Academy of Sciences of the United States of America, 114(15)

Metcalf CJE, Walter KS, Wesolowski A, Buckee CO, Shevliakova E, Tatem AJ, Boos WR, Weinberger DM, Pitzer VE. (2017). Identifying climate drivers of infectious disease dynamics: recent advances and challenges ahead. Proceedings. Biological sciences, 284(1860)

Wesolowski A, Zu Erbach-Schoenberg E, Tatem AJ, Lourenço C, Viboud C, Charu V, Eagle N, Engø-Monsen K, Qureshi T, Buckee CO, Metcalf CJE. (2017). Multinational patterns of seasonal asymmetry in human movement influence infectious disease dynamics. Nature communications, 8(1)

Chang HH, Worby CJ, Yeka A, Nankabirwa J, Kamya MR, Staedke SG, Dorsey G, Murphy M, Neafsey DE, Jeffreys AE, Hubbart C, Rockett KA, Amato R, Kwiatkowski DP, Buckee CO, Greenhouse B. (2017). THE REAL McCOIL: A method for the concurrent estimation of the complexity of infection and SNP allele frequency for malaria parasites. PLoS computational biology, 13(1)

Taylor AR, Schaffner SF, Cerqueira GC, Nkhoma SC, Anderson TJC, Sriprawat K, Pyae Phyo A, Nosten F, Neafsey DE, Buckee CO. (2017). Quantifying connectivity between local Plasmodium falciparum malaria parasite populations using identity by descent. PLoS genetics, 13(10)

Shaw WR, Marcenac P, Childs LM, Buckee CO, Baldini F, Sawadogo SP, Dabiré RK, Diabaté A, Catteruccia F. (2016). Wolbachia infections in natural Anopheles populations affect egg laying and negatively correlate with Plasmodium development. Nature communications, (7)

Buckee CO, Tatem AJ, Metcalf CJE. (2017). Seasonal Population Movements and the Surveillance and Control of Infectious Diseases. Trends in parasitology, 33(1)

Chang HH, Meibalan E, Zelin J, Daniels R, Eziefula AC, Meyer EC, Tadesse F, Grignard L, Joice RC, Drakeley C, Wirth DF, Volkman SK, Buckee C, Bousema T, Marti M. (2016). Persistence of Plasmodium falciparum parasitemia after artemisinin combination therapy: evidence from a randomized trial in Uganda. Scientific reports, (6)

Chang HH, Childs LM, Buckee CO. (2016). Variation in infection length and superinfection enhance selection efficiency in the human malaria parasite. Scientific reports, (6)

Obaldía N 3rd., Dow GS, Gerena L, Kyle D, Otero W, Mantel PY, Baro N, Daniels R, Mukherjee A, Childs LM, Buckee C, Duraisingh MT, Volkman SK, Wirth DF, Marti M. (2016). Altered drug susceptibility during host adaptation of a Plasmodium falciparum strain in a non-human primate model. Scientific reports, (6)

Wesolowski A, Mensah K, Brook CE, Andrianjafimasy M, Winter A, Buckee CO, Razafindratsimandresy R, Tatem AJ, Heraud JM, Metcalf CJ. (2016). Introduction of rubella-containing-vaccine to Madagascar: implications for roll-out and local elimination. Journal of the Royal Society, Interface, 13(117)

Wesolowski A, Buckee CO, Engø-Monsen K, Metcalf CJE. (2016). Connecting Mobility to Infectious Diseases: The Promise and Limits of Mobile Phone Data. The Journal of infectious diseases, 214(suppl_4)

Wesolowski A, Metcalf CJ, Eagle N, Kombich J, Grenfell BT, Bjørnstad ON, Lessler J, Tatem AJ, Buckee CO. (2015). Quantifying seasonal population fluxes driving rubella transmission dynamics using mobile phone data. Proceedings of the National Academy of Sciences of the United States of America, 112(35)

Childs LM, Buckee CO. (2015). Dissecting the determinants of malaria chronicity: why within-host models struggle to reproduce infection dynamics. Journal of the Royal Society, Interface, 12(104)

Larremore DB, Sundararaman SA, Liu W, Proto WR, Clauset A, Loy DE, Speede S, Plenderleith LJ, Sharp PM, Hahn BH, Rayner JC, Buckee CO. (2015). Ape parasite origins of human malaria virulence genes. Nature communications, (6)

Peak CM, Thuan PD, Britton A, Nguyen TD, Wolbers M, Thanh NV, Buckee CO, Boni MF. (2015). Measuring the association between artemisinin-based case management and malaria incidence in southern Vietnam, 1991-2010. The American journal of tropical medicine and hygiene, 92(4)

Wesolowski A, Qureshi T, Boni MF, Sundsøy PR, Johansson MA, Rasheed SB, Engø-Monsen K, Buckee CO. (2015). Impact of human mobility on the emergence of dengue epidemics in Pakistan. Proceedings of the National Academy of Sciences of the United States of America, 112(38)

Wesolowski A, O'Meara WP, Tatem AJ, Ndege S, Eagle N, Buckee CO. (2015). Quantifying the impact of accessibility on preventive healthcare in sub-Saharan Africa using mobile phone data. Epidemiology (Cambridge, Mass.), 26(2)

Watkins ER, Penman BS, Lourenço J, Buckee CO, Maiden MC, Gupta S. (2015). Vaccination Drives Changes in Metabolic and Virulence Profiles of Streptococcus pneumoniae. PLoS pathogens, 11(7)

Nilsson SK, Childs LM, Buckee C, Marti M. (2015). Targeting Human Transmission Biology for Malaria Elimination. PLoS pathogens, 11(6)

Childs LM, Abuelezam NN, Dye C, Gupta S, Murray MB, Williams BG, Buckee CO. (2015). Modelling challenges in context: lessons from malaria, HIV, and tuberculosis. Epidemics, (10)

Wesolowski A, O'Meara WP, Eagle N, Tatem AJ, Buckee CO. (2015). Evaluating Spatial Interaction Models for Regional Mobility in Sub-Saharan Africa. PLoS computational biology, 11(7)

Wesolowski A, Buckee CO, Bengtsson L, Wetter E, Lu X, Tatem AJ. (2014). Commentary: containing the ebola outbreak - the potential and challenge of mobile network data. PLoS currents, (6)

Wesolowski A, Stresman G, Eagle N, Stevenson J, Owaga C, Marube E, Bousema T, Drakeley C, Cox J, Buckee CO. (2014). Quantifying travel behavior for infectious disease research: a comparison of data from surveys and mobile phones. Scientific reports, (4)

Coleman BI, Skillman KM, Jiang RHY, Childs LM, Altenhofen LM, Ganter M, Leung Y, Goldowitz I, Kafsack BFC, Marti M, Llinás M, Buckee CO, Duraisingh MT. (2014). A Plasmodium falciparum histone deacetylase regulates antigenic variation and gametocyte conversion. Cell host & microbe, 16(2)

Watkins ER, Grad YH, Gupta S, Buckee CO. (2014). Contrasting within- and between-host immune selection shapes Neisseria Opa repertoires. Scientific reports, (4)

Bei AK, Diouf A, Miura K, Larremore DB, Ribacke U, Tullo G, Moss EL, Neafsey DE, Daniels RF, Zeituni AE, Nosamiefan I, Volkman SK, Ahouidi AD, Ndiaye D, Dieye T, Mboup S, Buckee CO, Long CA, Wirth DF. (2015). Immune characterization of Plasmodium falciparum parasites with a shared genetic signature in a region of decreasing transmission. Infection and immunity, 83(1)

Buckee CO. (2014). Society: Protect privacy of mobile data. Nature, 514(7520)

Lim C, Hansen E, DeSimone TM, Moreno Y, Junker K, Bei A, Brugnara C, Buckee CO, Duraisingh MT. Expansion of host cellular niche can drive adaptation of a zoonotic malaria parasite to humans. Nature communications, (4)

Hansen E, Buckee CO. (2013). Modeling the human infectious reservoir for malaria control: does heterogeneity matter?. Trends in parasitology, 29(6)

Larremore DB, Clauset A, Buckee CO. (2013). A network approach to analyzing highly recombinant malaria parasite genes. PLoS computational biology, 9(10)

Wesolowski A, Buckee CO, Pindolia DK, Eagle N, Smith DL, Garcia AJ, Tatem AJ. (2013). The use of census migration data to approximate human movement patterns across temporal scales. PLoS One, 8(1)

Buckee CO, Wesolowski A, Eagle NN, Hansen E, Snow RW. (2013). Mobile phones and malaria: modeling human and parasite travel. Travel medicine and infectious disease, 11(1)

Wesolowski A, Eagle N, Noor AM, Snow RW, Buckee CO. (2013). The impact of biases in mobile phone ownership on estimates of human mobility. Journal of the Royal Society, Interface, 10(81)

Salathé M, Bengtsson L, Bodnar TJ, Brewer DD, Brownstein JS, Buckee C, Campbell EM, Cattuto C, Khandelwal S, Mabry PL, Vespignani A. (2012). Digital epidemiology. PLoS computational biology, 8(7)

Wesolowski A, Eagle N, Noor AM, Snow RW, Buckee CO. (2012). Heterogeneous mobile phone ownership and usage patterns in Kenya. PLoS One, 7(4)

Penman BS, Gupta S, Buckee CO. (2012). The emergence and maintenance of sickle cell hotspots in the Mediterranean. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 12(7)

Wesolowski A, Eagle N, Tatem AJ, Smith DL, Noor AM, Snow RW, Buckee CO. (2012). Quantifying the impact of human mobility on malaria. Science (New York, N.Y.), 338(6104)

Buckee CO, Recker M. (2012). Evolution of the multi-domain structures of virulence genes in the human malaria parasite, Plasmodium falciparum. PLoS computational biology, 8(4)

Buckee CO, Recker M, Watkins ER, Gupta S. (2011). Role of stochastic processes in maintaining discrete strain structure in antigenically diverse pathogen populations. Proceedings of the National Academy of Sciences of the United States of America, 108(37)

Buckee CO, Gupta S, Kriz P, Maiden MC, Jolley KA. (2010). Long-term evolution of antigen repertoires among carried meningococci. Proceedings. Biological sciences, 277(1688)

Buckee CO, Gupta S. (2010). Modelling malaria population structure and its implications for control. Advances in experimental medicine and biology, (673)

Buckee CO, Jolley KA, Recker M, Penman B, Kriz P, Gupta S, Maiden MC. (2008). Role of selection in the emergence of lineages and the evolution of virulence in Neisseria meningitidis. Proceedings of the National Academy of Sciences of the United States of America, 105(39)

Recker M, Arinaminpathy N, Buckee CO. (2008). The effects of a partitioned var gene repertoire of Plasmodium falciparum on antigenic diversity and the acquisition of clinical immunity. Malaria journal, (7)

Buckee CO, Bull PC, Gupta S. (2009). Inferring malaria parasite population structure from serological networks. Proceedings. Biological sciences, 276(1656)

Buckee C, Danon L, Gupta S. (2007). Host community structure and the maintenance of pathogen diversity. Proceedings. Biological sciences, 274(1619)

Buckee CO, Koelle K, Mustard MJ, Gupta S. (2004). The effects of host contact network structure on pathogen diversity and strain structure. Proceedings of the National Academy of Sciences of the United States of America, 101(29)