Donald Burke

Distinguished University Professor of Health Science and Policy





Huang AT, Garcia-Carreras B, Hitchings MDT, Yang B, Katzelnick LC, Rattigan SM, Borgert BA, Moreno CA, Solomon BD, Rodriguez-Barraquer I, Lessler J, Salje H, Burke D, Wesolowski A, Cummings DAT. (2020). A systematic review of antibody mediated immunity to coronaviruses: antibody kinetics, correlates of protection, and association of antibody responses with severity of disease. medRxiv : the preprint server for health sciences

Jalal H, Buchanich JM, Sinclair DR, Roberts MS, Burke DS. (2020). Age and generational patterns of overdose death risk from opioids and other drugs. Nature medicine

Sinclair DR, Grefenstette JJ, Krauland MG, Galloway DD, Frankeny RJ, Travis C, Burke DS, Roberts MS. (2019). Forecasted Size of Measles Outbreaks Associated With Vaccination Exemptions for Schoolchildren. JAMA network open, 2(8)

Buchanich JM, Balmert LC, Williams KE, Burke DS. (2018). The Effect of Incomplete Death Certificates on Estimates of Unintentional Opioid-Related Overdose Deaths in the United States, 1999-2015. Public health reports (Washington, D.C. : 1974), 133(4)

Buchanich JM, Doerfler SM, Lann MF, Marsh GM, Burke DS. (2018). Improvement in racial disparities in years of life lost in the USA since 1990. PLoS One, 13(4)

Jalal H, Buchanich JM, Roberts MS, Balmert LC, Zhang K, Burke DS. (2018). Changing dynamics of the drug overdose epidemic in the United States from 1979 through 2016. Science (New York, N.Y.), 361(6408)

van Panhuis WG, Cross A, Burke DS. (2018). Project Tycho 2.0: a repository to improve the integration and reuse of data for global population health. Journal of the American Medical Informatics Association : JAMIA, 25(12)

España G, Grefenstette J, Perkins A, Torres C, Campo Carey A, Diaz H, de la Hoz F, Burke DS, van Panhuis WG. (2018). Exploring scenarios of chikungunya mitigation with a data-driven agent-based model of the 2014-2016 outbreak in Colombia. Scientific reports, 8(1)

Marques ETA, Burke DS. (2018). Tradition and innovation in development of a Zika vaccine. Lancet, 391(10120)

Gearhart TL, Montelaro RC, Schurdak ME, Pilcher CD, Rinaldo CR, Kodadek T, Park Y, Islam K, Yurko R, Marques ET Jr., Burke DS. (2016). Selection of a potential diagnostic biomarker for HIV infection from a random library of non-biological synthetic peptoid oligomers. Journal of immunological methods, (435)

Buchanich JM, Balmert LC, Pringle JL, Williams KE, Burke DS, Marsh GM. (2016). Patterns and trends in accidental poisoning death rates in the US, 1979-2014. Preventive medicine, (89)

Balmert LC, Buchanich JM, Pringle JL, Williams KE, Burke DS, Marsh GM. (2016). Patterns and Trends in Accidental Poisoning Deaths: Pennsylvania's Experience 1979-2014. PloS one, 11(3)

Burke DS. (2016). Forecasting the opioid epidemic. Science (New York, N.Y.), 354(6312)

Dalziel BD, Bjørnstad ON, van Panhuis WG, Burke DS, Metcalf CJ, Grenfell BT. (2016). Persistent Chaos of Measles Epidemics in the Prevaccination United States Caused by a Small Change in Seasonal Transmission Patterns. PLoS computational biology, 12(2)

van Panhuis WG, Choisy M, Xiong X, Chok NS, Akarasewi P, Iamsirithaworn S, Lam SK, Chong CK, Lam FC, Phommasak B, Vongphrachanh P, Bouaphanh K, Rekol H, Hien NT, Thai PQ, Duong TN, Chuang JH, Liu YL, Ng LC, Shi Y, Tayag EA, Roque VG Jr., Lee Suy LL, Jarman RG, Gibbons RV, Velasco JM, Yoon IK, Burke DS, Cummings DA. (2015). Region-wide synchrony and traveling waves of dengue across eight countries in Southeast Asia. Proceedings of the National Academy of Sciences of the United States of America, 112(42)

Rodriguez-Barraquer I, Mier-Y-Teran-Romero L, Ferguson N, Burke DS, Cummings DAT. (2015). Differential efficacy of dengue vaccine by immune status. Lancet, 385(9979)

Ruberto I, Marques E, Burke DS, Van Panhuis WG. (2015). The availability and consistency of dengue surveillance data provided online by the World Health Organization. PLoS neglected tropical diseases, 9(4)

Lukens S, DePasse J, Rosenfeld R, Ghedin E, Mochan E, Brown ST, Grefenstette J, Burke DS, Swigon D, Clermont G. (2014). A large-scale immuno-epidemiological simulation of influenza A epidemics. BMC public health, (14)

van Panhuis WG, Paul P, Emerson C, Grefenstette J, Wilder R, Herbst AJ, Heymann D, Burke DS. (2014). A systematic review of barriers to data sharing in public health. BMC Public Health, (14)

Rodriguez-Barraquer I, Mier-y-Teran-Romero L, Burke DS, Cummings DA. (2013). Challenges in the interpretation of dengue vaccine trial results. PLoS neglected tropical diseases, 7(8)

van Panhuis WG, Grefenstette J, Jung SY, Chok NS, Cross A, Eng H, Lee BY, Zadorozhny V, Brown S, Cummings D, Burke DS. (2013). Contagious diseases in the United States from 1888 to the present. The New England journal of medicine, 369(22)

Rodriguez-Barraquer I, Mier-y-Teran-Romero L, Schwartz IB, Burke DS, Cummings DA. (2014). Potential opportunities and perils of imperfect dengue vaccines. Vaccine, 32(4)

Azman AS, Stark JH, Althouse BM, Vukotich CJ Jr., Stebbins S, Burke DS, Cummings DA. (2013). Household transmission of influenza A and B in a school-based study of non-pharmaceutical interventions. Epidemics, 5(4)

Kumar S, Grefenstette JJ, Galloway D, Albert SM, Burke DS. (2014). Kumar et al. respond. American journal of public health, 104(1)

Kumar S, Grefenstette JJ, Galloway D, Albert SM, Burke DS. (2013). Policies to reduce influenza in the workplace: impact assessments using an agent-based model. American journal of public health, 103(8)

Burke DS, Grefenstette JJ. (2013). Toward an integrated meta-model of public health dynamics for preparedness decision support. Journal of public health management and practice : JPHMP, (19 Suppl 2)

Grefenstette JJ, Brown ST, Rosenfeld R, DePasse J, Stone NT, Cooley PC, Wheaton WD, Fyshe A, Galloway DD, Sriram A, Guclu H, Abraham T, Burke DS. (2013). FRED (a Framework for Reconstructing Epidemic Dynamics): an open-source software system for modeling infectious diseases and control strategies using census-based populations. BMC Public Health, (13)

Toner ES, Adalja AA, Nuzzo JB, Inglesby TV, Henderson DA, Burke DS. (2013). Assessment of serosurveys for H5N1. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 56(9)

Reich NG, Shrestha S, King AA, Rohani P, Lessler J, Kalayanarooj S, Yoon IK, Gibbons RV, Burke DS, Cummings DA. (2013). Interactions between serotypes of dengue highlight epidemiological impact of cross-immunity. Journal of the Royal Society, Interface, 10(86)

Yonas MA, Burke JG, Brown ST, Borrebach JD, Garland R, Burke DS, Grefenstette JJ. (2013). Dynamic simulation of crime perpetration and reporting to examine community intervention strategies. Health education & behavior : the official publication of the Society for Public Health Education, 40(1 Suppl)

Salje H, Lessler J, Endy TP, Curriero FC, Gibbons RV, Nisalak A, Nimmannitya S, Kalayanarooj S, Jarman RG, Thomas SJ, Burke DS, Cummings DA. (2012). Revealing the microscale spatial signature of dengue transmission and immunity in an urban population. Proceedings of the National Academy of Sciences of the United States of America, 109(24)

Stark JH, Sharma R, Ostroff S, Cummings DA, Ermentrout B, Stebbins S, Burke DS, Wisniewski SR. (2012). Local spatial and temporal processes of influenza in Pennsylvania, USA: 2003-2009. PloS one, 7(3)

Beatty M, Boni MF, Brown S, Buathong R, Burke D, Coudeville L, Cummings DA, Edelman R, Farrar J, Focks DA, Gomes MG, Guignard A, Halstead S, Hombach J, Knerer G, Koelle K, Lam FC, Lang J, Longini I, Medlock J, Namgyal P, Powell M, Recker M, Rohani P, Standaert B, Struchiner C, Teyssou R, Wearing H. (2012). Assessing the potential of a candidate dengue vaccine with mathematical modeling. PLoS neglected tropical diseases, 6(3)

Potter MA, Brown ST, Cooley PC, Sweeney PM, Hershey TB, Gleason SM, Lee BY, Keane CR, Grefenstette J, Burke DS. (2012). School closure as an influenza mitigation strategy: how variations in legal authority and plan criteria can alter the impact. BMC Public Health, (12)

Potter MA, Brown ST, Lee BY, Grefenstette J, Keane CR, Lin CJ, Quinn SC, Stebbins S, Sweeney PM, Burke DS. (2012). Preparedness for pandemics: does variation among states affect the nation as a whole?. Journal of public health management and practice : JPHMP, 18(3)

Lee BY, Assi TM, Rookkapan K, Connor DL, Rajgopal J, Sornsrivichai V, Brown ST, Welling JS, Norman BA, Chen SI, Bailey RR, Wiringa AE, Wateska AR, Jana A, Van Panhuis WG, Burke DS. (2011). Replacing the measles ten-dose vaccine presentation with the single-dose presentation in Thailand. Vaccine, 29(21)

Lee BY, Song Y, Bartsch SM, Kim DS, Singh A, Avery TR, Brown ST, Yilmaz SL, Wong KF, Potter MA, Burke DS, Platt R, Huang SS. (2011). Long-term care facilities: important participants of the acute care facility social network?. PLoS One, 6(12)

Lee BY, Assi TM, Rajgopal J, Norman BA, Chen SI, Brown ST, Slayton RB, Kone S, Kenea H, Welling JS, Connor DL, Wateska AR, Jana A, Wiringa AE, Van Panhuis WG, Burke DS. (2012). Impact of introducing the pneumococcal and rotavirus vaccines into the routine immunization program in Niger. American journal of public health, 102(2)

Shim E, Grefenstette JJ, Albert SM, Cakouros BE, Burke DS. (2012). A game dynamic model for vaccine skeptics and vaccine believers: measles as an example. Journal of theoretical biology, (295)

Stebbins S, Cummings DA, Stark JH, Vukotich C, Mitruka K, Thompson W, Rinaldo C, Roth L, Wagner M, Wisniewski SR, Dato V, Eng H, Burke DS. (2011). Reduction in the incidence of influenza A but not influenza B associated with use of hand sanitizer and cough hygiene in schools: a randomized controlled trial. The Pediatric infectious disease journal, 30(11)

Brown ST, Tai JH, Bailey RR, Cooley PC, Wheaton WD, Potter MA, Voorhees RE, LeJeune M, Grefenstette JJ, Burke DS, McGlone SM, Lee BY. (2011). Would school closure for the 2009 H1N1 influenza epidemic have been worth the cost?: a computational simulation of Pennsylvania. BMC Public Health, (11)

Lee BY, McGlone SM, Song Y, Avery TR, Eubank S, Chang CC, Bailey RR, Wagener DK, Burke DS, Platt R, Huang SS. (2011). Social network analysis of patient sharing among hospitals in Orange County, California. American journal of public health, 101(4)

Fraser C, Cummings DA, Klinkenberg D, Burke DS, Ferguson NM. (2011). Influenza transmission in households during the 1918 pandemic. American journal of epidemiology, 174(5)

Lee BY, Assi TM, Rookkapan K, Wateska AR, Rajgopal J, Sornsrivichai V, Chen SI, Brown ST, Welling J, Norman BA, Connor DL, Bailey RR, Jana A, Van Panhuis WG, Burke DS. (2011). Maintaining vaccine delivery following the introduction of the rotavirus and pneumococcal vaccines in Thailand. PLoS One, 6(9)

Lee BY, McGlone SM, Wong KF, Yilmaz SL, Avery TR, Song Y, Christie R, Eubank S, Brown ST, Epstein JM, Parker JI, Burke DS, Platt R, Huang SS. (2011). Modeling the spread of methicillin-resistant Staphylococcus aureus (MRSA) outbreaks throughout the hospitals in Orange County, California. Infection control and hospital epidemiology, 32(6)

Assi TM, Brown ST, Djibo A, Norman BA, Rajgopal J, Welling JS, Chen SI, Bailey RR, Kone S, Kenea H, Connor DL, Wateska AR, Jana A, Wisniewski SR, Van Panhuis WG, Burke DS, Lee BY. (2011). Impact of changing the measles vaccine vial size on Niger's vaccine supply chain: a computational model. BMC Public Health, (11)

Rajgopal J, Connor DL, Assi TM, Norman BA, Chen SI, Bailey RR, Long AR, Wateska AR, Bacon KM, Brown ST, Burke DS, Lee BY. (2011). The optimal number of routine vaccines to order at health clinics in low or middle income countries. Vaccine, 29(33)

Lee BY, Brown ST, Bailey RR, Zimmerman RK, Potter MA, McGlone SM, Cooley PC, Grefenstette JJ, Zimmer SM, Wheaton WD, Quinn SC, Voorhees RE, Burke DS. (2011). The benefits to all of ensuring equal and timely access to influenza vaccines in poor communities. Health affairs (Project Hope), 30(6)

Lee BY, Connor DL, Kitchen SB, Bacon KM, Shah M, Brown ST, Bailey RR, Laosiritaworn Y, Burke DS, Cummings DA. (2011). Economic value of dengue vaccine in Thailand. The American journal of tropical medicine and hygiene, 84(5)

Huang SS, Avery TR, Song Y, Elkins KR, Nguyen CC, Nutter SK, Nafday AA, Condon CJ, Chang MT, Chrest D, Boos J, Bobashev G, Wheaton W, Frank SA, Platt R, Lipsitch M, Bush RM, Eubank S, Burke DS, Lee BY. (2010). Quantifying interhospital patient sharing as a mechanism for infectious disease spread. Infection control and hospital epidemiology, 31(11)

Carr JK, Wolfe ND, Torimiro JN, Tamoufe U, Mpoudi-Ngole E, Eyzaguirre L, Birx DL, McCutchan FE, Burke DS. (2010). HIV-1 recombinants with multiple parental strains in low-prevalence, remote regions of Cameroon: evolutionary relics?. Retrovirology, (7)

van Panhuis WG, Gibbons RV, Endy TP, Rothman AL, Srikiatkhachorn A, Nisalak A, Burke DS, Cummings DA. (2010). Inferring the serotype associated with dengue virus infections on the basis of pre- and postinfection neutralizing antibody titers. The Journal of infectious diseases, 202(7)

Lee BY, Brown ST, Cooley P, Grefenstette JJ, Zimmerman RK, Zimmer SM, Potter MA, Rosenfeld R, Wheaton WD, Wiringa AE, Bacon KM, Burke DS. (2010). Vaccination deep into a pandemic wave potential mechanisms for a "third wave" and the impact of vaccination. American journal of preventive medicine, 39(5)

Lee BY, Norman BA, Assi TM, Chen SI, Bailey RR, Rajgopal J, Brown ST, Wiringa AE, Burke DS. (2010). Single versus multi-dose vaccine vials: an economic computational model. Vaccine, 28(32)

Lee BY, Brown ST, Korch GW, Cooley PC, Zimmerman RK, Wheaton WD, Zimmer SM, Grefenstette JJ, Bailey RR, Assi TM, Burke DS. (2010). A computer simulation of vaccine prioritization, allocation, and rationing during the 2009 H1N1 influenza pandemic. Vaccine, 28(31)

Cooley P, Lee BY, Brown S, Cajka J, Chasteen B, Ganapathi L, Stark JH, Wheaton WD, Wagener DK, Burke DS. (2010). Protecting health care workers: a pandemic simulation based on Allegheny County. Influenza and other respiratory viruses, 4(2)

Yang Y, Halloran ME, Daniels MJ, Longini IM Jr., Burke DS, Cummings DA. (2010). Modeling Competing Infectious Pathogens from a Bayesian Perspective: Application to Influenza Studies with Incomplete Laboratory Results. Journal of the American Statistical Association, 105(492)

Lee BY, Brown ST, Cooley PC, Zimmerman RK, Wheaton WD, Zimmer SM, Grefenstette JJ, Assi TM, Furphy TJ, Wagener DK, Burke DS. (2010). A computer simulation of employee vaccination to mitigate an influenza epidemic. American journal of preventive medicine, 38(3)

Lee BY, Burke DS. (2010). Constructing target product profiles (TPPs) to help vaccines overcome post-approval obstacles. Vaccine, 28(16)

Lee BY, Brown ST, Cooley P, Potter MA, Wheaton WD, Voorhees RE, Stebbins S, Grefenstette JJ, Zimmer SM, Zimmerman RK, Assi TM, Bailey RR, Wagener DK, Burke DS. (2010). Simulating school closure strategies to mitigate an influenza epidemic. Journal of public health management and practice : JPHMP, 16(3)

Burke DS, Russell J, Cerqueira MT, Conley KM, Eggleston MM, Koo D, Lewis AL, Lee AF, Pearson CE, Pestronk RM, Schwartz B, Smith WA. (2009). Comments from the field on the Galway Consensus Conference Statement. Health education & behavior : the official publication of the Society for Public Health Education, 36(3)

Cummings DA, Iamsirithaworn S, Lessler JT, McDermott A, Prasanthong R, Nisalak A, Jarman RG, Burke DS, Gibbons RV. (2009). The impact of the demographic transition on dengue in Thailand: insights from a statistical analysis and mathematical modeling. PLoS medicine, 6(9)

Zimmer SM, Burke DS. (2009). Historical perspective--Emergence of influenza A (H1N1) viruses. The New England journal of medicine, 361(3)

Halloran ME, Ferguson NM, Eubank S, Longini IM Jr., Cummings DA, Lewis B, Xu S, Fraser C, Vullikanti A, Germann TC, Wagener D, Beckman R, Kadau K, Barrett C, Macken CA, Burke DS, Cooley P. (2008). Modeling targeted layered containment of an influenza pandemic in the United States. Proceedings of the National Academy of Sciences of the United States of America, 105(12)

Parmanto B, Paramita MV, Sugiantara W, Pramana G, Scotch M, Burke DS. (2008). Spatial and multidimensional visualization of Indonesia's village health statistics. International journal of health geographics, (7)

Bidez MW, Cochran JE Jr., King D, Burke DS 3rd.. (2007). Occupant dynamics in rollover crashes: influence of roof deformation and seat belt performance on probable spinal column injury. Annals of biomedical engineering, 35(11)

Lessler J, Cummings DA, Fishman S, Vora A, Burke DS. (2007). Transmissibility of swine flu at Fort Dix, 1976. Journal of the Royal Society, Interface, 4(15)

Billings L, Schwartz IB, Shaw LB, McCrary M, Burke DS, Cummings DA. (2007). Instabilities in multiserotype disease models with antibody-dependent enhancement. Journal of theoretical biology, 246(1)

Ferguson NM, Cummings DA, Fraser C, Cajka JC, Cooley PC, Burke DS. (2006). Strategies for mitigating an influenza pandemic. Nature, 442(7101)

Ockenhouse CF, Hu WC, Kester KE, Cummings JF, Stewart A, Heppner DG, Jedlicka AE, Scott AL, Wolfe ND, Vahey M, Burke DS. (2006). Common and divergent immune response signaling pathways discovered in peripheral blood mononuclear cell gene expression patterns in presymptomatic and clinically apparent malaria. Infection and immunity, 74(10)

Burke DS, Kliks S. (2006). Antibody-dependent enhancement in dengue virus infections. The Journal of infectious diseases, 193(4)

Longini IM Jr., Halloran ME, Nizam A, Yang Y, Xu S, Burke DS, Cummings DA, Epstein JM. (2007). Containing a large bioterrorist smallpox attack: a computer simulation approach. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 11(2)

Burke DS, Epstein JM, Cummings DA, Parker JI, Cline KC, Singa RM, Chakravarty S. (2006). Individual-based computational modeling of smallpox epidemic control strategies. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 13(11)

Cummings DA, Schwartz IB, Billings L, Shaw LB, Burke DS. (2005). Dynamic effects of antibody-dependent enhancement on the fitness of viruses. Proceedings of the National Academy of Sciences of the United States of America, 102(42)

Cummings DA, Moss WJ, Long K, Wiysonge CS, Muluh TJ, Kollo B, Nomo E, Wolfe ND, Burke DS. (2006). Improved measles surveillance in Cameroon reveals two major dynamic patterns of incidence. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 10(2)

Ferguson NM, Cummings DA, Cauchemez S, Fraser C, Riley S, Meeyai A, Iamsirithaworn S, Burke DS. (2005). Strategies for containing an emerging influenza pandemic in Southeast Asia. Nature, 437(7056)

Schwartz IB, Shaw LB, Cummings DA, Billings L, McCrary M, Burke DS. (2005). Chaotic desynchronization of multistrain diseases. Physical review. E, Statistical, nonlinear, and soft matter physics, 72(6 Pt 2)

Wolfe ND, Daszak P, Kilpatrick AM, Burke DS. (2005). Bushmeat hunting, deforestation, and prediction of zoonoses emergence. Emerging infectious diseases, 11(12)

Cummings DA, Irizarry RA, Huang NE, Endy TP, Nisalak A, Ungchusak K, Burke DS. (2004). Travelling waves in the occurrence of dengue haemorrhagic fever in Thailand. Nature, 427(6972)

Burke DS. (2004). Lessons learned from the 1954 Field Trial of Poliomyelitis Vaccine. Clinical trials (London, England), 1(1)

Wolfe ND, Prosser TA, Carr JK, Tamoufe U, Mpoudi-Ngole E, Torimiro JN, LeBreton M, McCutchan FE, Birx DL, Burke DS. (2004). Exposure to nonhuman primates in rural Cameroon. Emerging infectious diseases, 10(12)

Waters HR, Dougherty L, Tegang SP, Tran N, Wiysonge CS, Long K, Wolfe ND, Burke DS. (2004). Coverage and costs of childhood immunizations in Cameroon. Bulletin of the World Health Organization, 82(9)

Burke DS. (1976). Cardiac Monitor Malfunction Simulating Bizarre Rhythm. Postgraduate medicine, 60(3)