Edward Goldstein

Senior Research Scientist





National Institutes of Health, National Institute of General Medical Sciences
People: Laura White, Ted Cohen, William Hanage, Rene Niehus, Ben Cowling, Tyler Brown, Joseph Wu, Mauricio Santillana Guzman, Joseph Lewnard, Aimee Taylor, Ayesha Mahmud, Pablo Martinez de Salazar, Lerato Magosi, Edward Goldstein, Christine Tedijanto, Tigist Menkir, Sze Man Leung, Hsiao-Han Chang, Caroline Buckee, Pamela Martinez, Marc Lipsitch
2009 – 2020

Read More »


Accorsi EK, Qiu X, Rumpler E, Kennedy-Shaffer L, Kahn R, Joshi K, Goldstein E, Stensrud MJ, Niehus R, Cevik M, Lipsitch M. (2021). How to detect and reduce potential sources of biases in studies of SARS-CoV-2 and COVID-19. European journal of epidemiology

Goldstein E. (2021). Rise in the prevalence of resistance to extended-spectrum cephalosporins in the USA, nursing homes and antibiotic prescribing in outpatient and inpatient settings. The Journal of antimicrobial chemotherapy

Stern D, Lajous M, De la Rosa B, Goldstein E. (2021). On the increasing incidence of SARS-CoV- 2 in older adolescents and younger adults during the epidemic in Mexico. Salud publica de Mexico, 63(3 May-Jun)

Goldstein E, Lipsitch M, Cevik M. (2021). On the Effect of Age on the Transmission of SARS-CoV-2 in Households, Schools, and the Community. The Journal of infectious diseases, 223(3)

Finelli L, Choi Y, Goldstein E. (2020). Number needed to immunize to prevent RSV with extended half-life monoclonal antibody. Vaccine

Goldstein E, Lipsitch M. (2020). The relation between prescribing of different antibiotics and rates of mortality with sepsis in US adults. BMC infectious diseases, 20(1)

Stern D, Lajous M, De la Rosa B, Goldstein E. (2020). On the increasing role of older adolescents and younger adults during the SARSCoV2 epidemic in Mexico. medRxiv : the preprint server for health sciences

Kissler SM, Tedijanto C, Goldstein E, Grad YH, Lipsitch M. (2020). Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period. Science (New York, N.Y.)

Goldstein E, Lipsitch M. (2020). Temporal rise in the proportion of both younger adults and older adolescents among COVID-19 cases in Germany: evidence of lesser adherence to social distancing practices?. medRxiv : the preprint server for health sciences

Martinez de Salazar P, Gomez-Barroso D, Pampaka D, Gil JM, Penalver B, Fernandez-Escobar C, Lipsitch M, Larrauri A, Goldstein E, Hernan M. (2020). Lockdown measures and relative changes in the age-specific incidence of SARS-CoV-2 in Spain. medRxiv : the preprint server for health sciences

Goldstein E, Lipsitch M. (2020). Temporal rise in the proportion of younger adults and older adolescents among coronavirus disease (COVID-19) cases following the introduction of physical distancing measures, Germany, March to April 2020. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 25(17)

Kissler Stephen M, Tedijanto Christine, Goldstein Edward, Grad Yonatan H., Lipsitch Marc. (2020). Projecting the transmission dynamics of SARS-CoV-2 through the post-pandemic period. Cold Spring Harbor Laboratory Press

Goldstein E, Finelli L, O'Halloran A, Liu P, Karaca Z, Steiner CA, Viboud C, Lipsitch M. (2019). Hospitalizations Associated with Respiratory Syncytial Virus and Influenza in Children, Including Children Diagnosed with Asthma. Epidemiology (Cambridge, Mass.), 30(6)

Goldstein E. (2019). Rise in mortality involving poisoning by medicaments other than narcotics, including poisoning by psychotropic drugs in different age/racial groups in the US. PLoS One, 14(7)

Goldstein E, Olesen SW, Karaca Z, Steiner CA, Viboud C, Lipsitch M. (2019). Levels of outpatient prescribing for four major antibiotic classes and rates of septicemia hospitalization in adults in different US states - a statistical analysis. BMC Public Health, 19(1)

Goldstein E, MacFadden DR, Karaca Z, Steiner CA, Viboud C, Lipsitch M. (2019). Antimicrobial resistance prevalence, rates of hospitalization with septicemia and rates of mortality with sepsis in adults in different US states. International journal of antimicrobial agents, 54(1)

Wong JY, Goldstein E, Fang VJ, Cowling BJ, Wu P. (2019). Real-time estimation of the influenza-associated excess mortality in Hong Kong. Epidemiology and infection, (147)

Mahmoud AS, Lipsitch M, Goldstein E. (2019). On the role of different age groups during pertussis epidemics in California, 2010 and 2014. Epidemiology and Infection, (147)

Goldstein E, Worby CJ, Lipsitch M. (2018). On the Role of Different Age Groups and Pertussis Vaccines During the 2012 Outbreak in Wisconsin. Open forum infectious diseases, 5(5)

Goldstein E, Nguyen HH, Liu P, Viboud C, Steiner CA, Worby CJ, Lipsitch M. (2018). On the Relative Role of Different Age Groups During Epidemics Associated With Respiratory Syncytial Virus. The Journal of infectious diseases, 217(2)

Worby CJ, Wallinga J, Lipsitch M, Goldstein E. (2017). Population effect of influenza vaccination under co-circulation of non-vaccine variants and the case for a bivalent A/H3N2 vaccine component. Epidemics, (19)

Goldstein E, Pitzer VE, O'Hagan JJ, Lipsitch M. (2017). Temporally Varying Relative Risks for Infectious Diseases: Implications for Infectious Disease Control. Epidemiology (Cambridge, Mass.), 28(1)

Hill AL, Rosenbloom DI, Goldstein E, Hanhauser E, Kuritzkes DR, Siliciano RF, Henrich TJ. (2016). Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV. PLoS pathogens, 12(4)

Patterson-Lomba O, Goldstein E, Gómez-Liévano A, Castillo-Chavez C, Towers S. (2015). Per capita incidence of sexually transmitted infections increases systematically with urban population size: a cross-sectional study. Sexually transmitted infections, 91(8)

Park M, Wu P, Goldstein E, Joo Kim W, Cowling BJ. (2016). Influenza-Associated Excess Mortality in South Korea. American journal of preventive medicine, 50(4)

Worby CJ, Chaves SS, Wallinga J, Lipsitch M, Finelli L, Goldstein E. (2015). On the relative role of different age groups in influenza epidemics. Epidemics, (13)

Goldstein E, Greene SK, Olson DR, Hanage WP, Lipsitch M. (2015). Estimating the hospitalization burden associated with influenza and respiratory syncytial virus in New York City, 2003-2011. Influenza and other respiratory viruses, 9(5)

Worby CJ, Kenyon C, Lynfield R, Lipsitch M, Goldstein E. (2015). Examining the role of different age groups, and of vaccination during the 2012 Minnesota pertussis outbreak. Scientific reports, (5)

Chunara R, Goldstein E, Patterson-Lomba O, Brownstein JS. (2015). Estimating influenza attack rates in the United States using a participatory cohort. Scientific reports, (5)

Grad YH, Goldstein E, Lipsitch M, White PJ. (2016). Improving Control of Antibiotic-Resistant Gonorrhea by Integrating Research Agendas Across Disciplines: Key Questions Arising From Mathematical Modeling. The Journal of infectious diseases, 213(6)

Grad YH, Kirkcaldy RD, Trees D, Dordel J, Harris SR, Goldstein E, Weinstock H, Parkhill J, Hanage WP, Bentley S, Lipsitch M. (2014). Genomic epidemiology of Neisseria gonorrhoeae with reduced susceptibility to cefixime in the USA: a retrospective observational study. The Lancet. Infectious diseases, 14(3)

Patterson-Lomba O, Van Noort S, Cowling BJ, Wallinga J, Gomes MG, Lipsitch M, Goldstein E. (2014). Utilizing syndromic surveillance data for estimating levels of influenza circulation. American journal of epidemiology, 179(11)

Huang KE, Lipsitch M, Shaman J, Goldstein E. (2014). The US 2009 A(H1N1) influenza epidemic: quantifying the impact of school openings on the reproductive number. Epidemiology (Cambridge, Mass.), 25(2)

Wu P, Goldstein E, Ho LM, Wu JT, Tsang T, Leung GM, Cowling BJ. (2014). Excess mortality impact of two epidemics of pandemic influenza A(H1N1pdm09) virus in Hong Kong. Influenza and other respiratory viruses, 8(1)

Wong JY, Wu P, Nishiura H, Goldstein E, Lau EH, Yang L, Chuang SK, Tsang T, Peiris JS, Wu JT, Cowling BJ. (2013). Infection fatality risk of the pandemic A(H1N1)2009 virus in Hong Kong. American journal of epidemiology, 177(8)

Quandelacy TM, Viboud C, Charu V, Lipsitch M, Goldstein E. (2014). Age- and sex-related risk factors for influenza-associated mortality in the United States between 1997-2007. American journal of epidemiology, 179(2)

Goldstein E, Kirkcaldy RD, Reshef D, Berman S, Weinstock H, Sabeti P, Del Rio C, Hall G, Hook EW, Lipsitch M. (2012). Factors related to increasing prevalence of resistance to ciprofloxacin and other antimicrobial drugs in Neisseria gonorrhoeae, United States. Emerging infectious diseases, 18(8)

Goldstein E, Viboud C, Charu V, Lipsitch M. (2012). Improving the estimation of influenza-related mortality over a seasonal baseline. Epidemiology (Cambridge, Mass.), 23(6)

Wu P, Goldstein E, Ho LM, Yang L, Nishiura H, Wu JT, Ip DK, Chuang SK, Tsang T, Cowling BJ. (2012). Excess mortality associated with influenza A and B virus in Hong Kong, 1998-2009. The Journal of infectious diseases, 206(12)

Goldstein E, Cowling BJ, Aiello AE, Takahashi S, King G, Lu Y, Lipsitch M. (2011). Estimating incidence curves of several infections using symptom surveillance data. PLoS One, 6(8)

Goldstein E, Cobey S, Takahashi S, Miller JC, Lipsitch M. (2011). Predicting the epidemic sizes of influenza A/H1N1, A/H3N2, and B: a statistical method. PLoS medicine, 8(7)

Lajous M, Danon L, López-Ridaura R, Astley CM, Miller JC, Dowell SF, O'Hagan JJ, Goldstein E, Lipsitch M. (2010). Mobile messaging as surveillance tool during pandemic (H1N1) 2009, Mexico. Emerging infectious diseases, 16(9)

Goldstein E, Miller JC, O'Hagan JJ, Lipsitch M. (2010). Pre-dispensing of antivirals to high-risk individuals in an influenza pandemic. Influenza and other respiratory viruses, 4(2)

Goldstein E, Cowling BJ, O'Hagan JJ, Danon L, Fang VJ, Hagy A, Miller JC, Reshef D, Robins J, Biedrzycki P, Lipsitch M. (2010). Oseltamivir for treatment and prevention of pandemic influenza A/H1N1 virus infection in households, Milwaukee, 2009. BMC infectious diseases, (10)

Shaman J, Goldstein E, Lipsitch M. (2011). Absolute humidity and pandemic versus epidemic influenza. American journal of epidemiology, 173(2)

Miller JC, Danon L, O'Hagan JJ, Goldstein E, Lajous M, Lipsitch M. (2010). Student behavior during a school closure caused by pandemic influenza A/H1N1. PLoS One, 5(5)

Goldstein E, Lipsitch M. (2009). Antiviral usage for H1N1 treatment: pros, cons and an argument for broader prescribing guidelines in the United States. PLoS currents, (1)

Colijn C, Cohen T, Fraser C, Hanage W, Goldstein E, Givon-Lavi N, Dagan R, Lipsitch M. (2010). What is the mechanism for persistent coexistence of drug-susceptible and drug-resistant strains of Streptococcus pneumoniae?. Journal of the Royal Society, Interface, 7(47)

Goldstein E, Lipsitch M. (2009). H1N1 vaccination and adults with underlying health conditions in the US. PLoS currents, (1)

Goldstein E, Dushoff J, Ma J, Plotkin JB, Earn DJ, Lipsitch M. (2009). Reconstructing influenza incidence by deconvolution of daily mortality time series. Proceedings of the National Academy of Sciences of the United States of America, 106(51)

Goldstein E, Miller JC, O'Hagan J, Lipsitch M. (2009). Predispensing of antivirals to high-risk individuals in an influenza pandemic. PLoS currents, (1)

Lipsitch M, Lajous M, O'Hagan JJ, Cohen T, Miller JC, Goldstein E, Danon L, Wallinga J, Riley S, Dowell SF, Reed C, McCarron M. (2009). Use of cumulative incidence of novel influenza A/H1N1 in foreign travelers to estimate lower bounds on cumulative incidence in Mexico. PLoS One, 4(9)

If you’d like to update your profile, please email modifications to

This site is registered on as a development site.