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Grant Lythe

Professor of Applied Mathematics

Education

Affiliations

Projects

Papers

Wilmes S, Jeffrey PA, Martinez-Fabregas J, Hafer M, Fyfe PK, Pohler E, Gaggero S, López-García M, Lythe G, Taylor C, Guerrier T, Launay D, Mitra S, Piehler J, Molina-París C, Moraga I. (2021). Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses. eLife, (10)

Truong VT, Baverel PG, Lythe GD, Vicini P, Yates JWT, Dubois VFS. (2021). Step-by-step comparison of ordinary differential equation and agent-based approaches to pharmacokinetic-pharmacodynamic models. CPT: pharmacometrics & systems pharmacology

Castro M, Lythe G, Smit J, Molina-París C. (2021). Fusion and fission events regulate endosome maturation and viral escape. Scientific reports, 11(1)

Carruthers J, Lythe G, López-García M, Gillard J, Laws TR, Lukaszewski R, Molina-París C. (2020). Stochastic dynamics of Francisella tularensis infection and replication. PLoS computational biology, 16(6)

Liao LE, Carruthers J, Smither SJ, , Weller SA, Williamson D, Laws TR, García-Dorival I, Hiscox J, Holder BP, Beauchemin CAA, Perelson AS, López-García M, Lythe G, Barr JN, Molina-París C. (2020). Quantification of Ebola virus replication kinetics in vitro. PLoS computational biology, 16(11)

de la Higuera L, López-García M, Castro M, Abourashchi N, Lythe G, Molina-París C. (2019). Fate of a Naive T Cell: A Stochastic Journey. Frontiers in immunology, (10)

Lythe G, Molina-París C. (2018). Some deterministic and stochastic mathematical models of naïve T-cell homeostasis. Immunological reviews, 285(1)

Castro M, López-García M, Lythe G, Molina-París C. (2018). First passage events in biological systems with non-exponential inter-event times. Scientific reports, 8(1)

Carruthers J, López-García M, Gillard JJ, Laws TR, Lythe G, Molina-París C. (2018). Infection to Predict Risk of Infection in a Laboratory. Frontiers in microbiology, (9)

Gonçalves P, Ferrarini M, Molina-Paris C, Lythe G, Vasseur F, Lim A, Rocha B, Azogui O. (2017). T cell repertoire: the selection for full diversity. Molecular immunology, (85)

Chu HH, Chan SW, Gosling JP, Blanchard N, Tsitsiklis A, Lythe G, Shastri N, Molina-París C, Robey EA. (2016). Continuous Effector CD8(+) T Cell Production in a Controlled Persistent Infection Is Sustained by a Proliferative Intermediate Population. Immunity, 45(1)

Donovan GM, Lythe G. (2016). T cell and reticular network co-dependence in HIV infection. Journal of theoretical biology, (395)

Castro M, Lythe G, Molina-París C, Ribeiro RM. (2016). Mathematics in modern immunology. Interface focus, 6(2)

Pham K, Shimoni R, Charnley M, Ludford-Menting MJ, Hawkins ED, Ramsbottom K, Oliaro J, Izon D, Ting SB, Reynolds J, Lythe G, Molina-Paris C, Melichar H, Robey E, Humbert PO, Gu M, Russell SM. (2015). Asymmetric cell division during T cell development controls downstream fate. The Journal of cell biology, 210(6)

Lythe G, Callard RE, Hoare RL, Molina-París C. (2016). How many TCR clonotypes does a body maintain?. Journal of theoretical biology, (389)

Castro M, van Santen HM, Férez M, Alarcón B, Lythe G, Molina-París C. (2014). Receptor Pre-Clustering and T cell Responses: Insights into Molecular Mechanisms. Frontiers in immunology, (5)

Sawicka M, Stritesky GL, Reynolds J, Abourashchi N, Lythe G, Molina-París C, Hogquist KA. (2014). From pre-DP, post-DP, SP4, and SP8 Thymocyte Cell Counts to a Dynamical Model of Cortical and Medullary Selection. Frontiers in immunology, (5)

Gillard JJ, Laws TR, Lythe G, Molina-París C. (2014). Modeling early events in Francisella tularensis pathogenesis. Frontiers in cellular and infection microbiology, (4)

Reynolds J, Amado IF, Freitas AA, Lythe G, Molina-París C. (2014). A mathematical perspective on CD4(+) T cell quorum-sensing. Journal of theoretical biology, (347)

Reynolds J, Coles M, Lythe G, Molina-París C. (2013). Mathematical Model of Naive T Cell Division and Survival IL-7 Thresholds. Frontiers in immunology, (4)

Lythe G, Mertens FG. (2003). Rice's ansatz for overdamped phi4 kinks at finite temperature. Physical review. E, Statistical, nonlinear, and soft matter physics, 67(2 Pt 2)

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