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Hana Dobrovolny

Bio

I received a B.Sc. in Physics and Mathematics from the University of Winnipeg, followed by an M.Sc in Physics from Bryn Mawr College and a Ph.D in Physics from Duke University. I started research in modeling of infectious diseases as a postdoc at Ryerson University and have continued this research as faculty at Texas Christian University..

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United States

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Papers

Makam S, Dobrovolny HM. (2026). Mathematical Modeling of the Role of Cytokines in Sindbis Virus Treatment of Glioblastoma. CPT: pharmacometrics & systems pharmacology, 15(2)

Dobrovolny HM. Mathematical Modeling of Cell-Cell Fusion Assays to Characterize Virus-Mediated Cell Fusion. Advances in experimental medicine and biology, (1509)

Sage H, Dobrovolny HM. (2026). Exploring the effect of density dependent infection rate in a within host viral infection model. Mathematical biosciences and engineering : MBE, 23(6)

Chiarelli A, Dobrovolny HM. (2026). A mathematical model for temperature effects on virus-mediated cell fusion. Journal of theoretical biology

Dobrovolny HM. (2025). How do viruses get around? A review of mathematical modeling of in-host viral transmission. Virology, (604)

Beach I, Dobrovolny HM. (2025). The Effect of Antibodies in the Presence of Syncytia During Viral Infections. Bulletin of mathematical biology, 87(6)

Gerg A, Dobrovolny HM. (2025). Quantifying Impact of HIV Receptor Surface Density Reveals Differences in Fusion Dynamics of HIV Strains. Viruses, 17(4)

Satani S, Suri A, Dobrovolny H. (2025). Mathematical modelling of oncolytic vaccinia virus therapy highlights neutrophil impact on tumour suppression. Journal of the Royal Society, Interface, 22(233)

Srivastava S, Dobrovolny HM. (2025). Quantitative analysis of respiratory viral triple infections: Examining within host dynamics of Influenza, RSV, and SARS-CoV-2. Mathematical biosciences and engineering : MBE, 22(11)

McCarthy G, Dobrovolny HM. (2025). Determining the best mathematical model for implementation of non-pharmaceutical interventions. Mathematical biosciences and engineering : MBE, 22(3)

Suri A, Satani S, Dobrovolny HM. (2025). Analyzing Differences in Viral Dynamics Between Vaccinated and Unvaccinated RSV Patients. Epidemiologia (Basel, Switzerland), 6(2)

Chiarelli A, Dobrovolny H. (2024). Viral Rebound After Antiviral Treatment: A Mathematical Modeling Study of the Role of Antiviral Mechanism of Action. Interdisciplinary sciences, computational life sciences

Noffel Z, Dobrovolny H. (2024). Modeling the bystander effect during viral coinfection. Journal of theoretical biology

Amidei A, Dobrovolny HM. (2024). Virus-mediated cell fusion of SARS-CoV-2 variants. Mathematical biosciences, (369)

González-Parra G, Dobrovolny HM. (2024). Editorial: Mathematical foundations in biological modelling and simulation. Mathematical biosciences and engineering : MBE, 21(9)

Glaschke S, Dobrovolny HM. (2024). Spatiotemporal spread of oncolytic virus in a heterogeneous cell population. Computers in biology and medicine, (183)

Polavarapu N, Doty M, Dobrovolny HM. (2024). Exploring the treatment of SARS-CoV-2 with modified vesicular stomatitis virus. Journal of theoretical biology

Noffel Z, Dobrovolny HM. (2023). Quantifying the effect of defective viral genomes in respiratory syncytial virus infections. Mathematical biosciences and engineering : MBE, 20(7)

Guo E, Dobrovolny HM. (2023). Mathematical Modeling of Oncolytic Virus Therapy Reveals Role of the Immune Response. Viruses, 15(9)

Dobrovolny HM. Mathematical Modeling of Virus-Mediated Syncytia Formation: Past Successes and Future Directions. Results and problems in cell differentiation, (71)

Buntval K, Dobrovolny HM. (2023). Modeling of oncolytic viruses in a heterogeneous cell population to predict spread into non-cancerous cells. Computers in biology and medicine, (165)

Gadiyar I, Dobrovolny HM. (2023). Different routes of infection of H5N1 lead to changes in infecting time. Mathematical biosciences

Alexander P, Dobrovolny HM. (2022). Treatment of Respiratory Viral Coinfections. Epidemiologia (Basel, Switzerland), 3(1)

Amidei A, Dobrovolny HM. (2022). Estimation of virus-mediated cell fusion rate of SARS-CoV-2. Virology, (575)

Pinky L, Dobrovolny HM. (2022). Epidemiological Consequences of Viral Interference: A Mathematical Modeling Study of Two Interacting Viruses. Frontiers in microbiology, (13)

Haun A, Fain B, Dobrovolny HM. (2023). Effect of cellular regeneration and viral transmission mode on viral spread. Journal of theoretical biology, (558)

Karr J, Malik-Sheriff RS, Osborne J, Gonzalez-Parra G, Forgoston E, Bowness R, Liu Y, Thompson R, Garira W, Barhak J, Rice J, Torres M, Dobrovolny HM, Tang T, Waites W, Glazier JA, Faeder JR, Kulesza A. (2022). Model Integration in Computational Biology: The Role of Reproducibility, Credibility and Utility. Frontiers in systems biology, (2)

Khan S, Dobrovolny HM. (2021). A study of the effects of age on the dynamics of RSV in animal models. Virus research, (304)

Rodriguez T, Dobrovolny HM. (2021). Quantifying the effect of trypsin and elastase on in vitro SARS-CoV infections. Virus research, (299)

Jessie B, Dobrovolny HM. (2021). The role of syncytia during viral infections. Journal of theoretical biology, (525)

Frieler M, Pho C, Lee BH, Dobrovolny H, Akkaraju GR, Naumov AV. (2021). Effects of Doxorubicin Delivery by Nitrogen-Doped Graphene Quantum Dots on Cancer Cell Growth: Experimental Study and Mathematical Modeling. Nanomaterials (Basel, Switzerland), 11(1)

Pho C, Frieler M, Akkaraju GR, Naumov AV, Dobrovolny HM. (2021). Using mathematical modeling to estimate time-independent cancer chemotherapy efficacy parameters. In silico pharmacology, 10(1)

Rodriguez T, Dobrovolny HM. (2021). Estimation of viral kinetics model parameters in young and aged SARS-CoV-2 infected macaques. Royal Society open science, 8(11)

Schmid H, Dobrovolny HM. (2020). An approximate solution of the interferon-dependent viral kinetics model of influenza. Journal of theoretical biology, (498)

Pinky L, Dobrovolny HM. (2020). SARS-CoV-2 coinfections: Could influenza and the common cold be beneficial?. Journal of medical virology, 92(11)

Fain B, Dobrovolny HM. (2020). Initial Inoculum and the Severity of COVID-19: A Mathematical Modeling Study of the Dose-Response of SARS-CoV-2 Infections. Epidemiologia (Basel, Switzerland), 1(1)

Murphy H, McCarthy G, Dobrovolny HM. (2020). Understanding the effect of measurement time on drug characterization. PloS one, 15(5)

Dobrovolny HM. (2020). Modeling the role of asymptomatics in infection spread with application to SARS-CoV-2. PloS one, 15(8)

Rowell CER, Dobrovolny HM. (2020). Energy Requirements for Loss of Viral Infectivity. Food and environmental virology, 12(4)

Dobrovolny HM. (2020). Quantifying the effect of remdesivir in rhesus macaques infected with SARS-CoV-2. Virology, (550)

González-Parra G, Dobrovolny HM. (2019). The rate of viral transfer between upper and lower respiratory tracts determines RSV illness duration. Journal of mathematical biology, 79(2)

Pinky L, Gonzalez-Parra G, Dobrovolny HM. (2019). Effect of stochasticity on coinfection dynamics of respiratory viruses. BMC bioinformatics, 20(1)

Pinky L, González-Parra G, Dobrovolny HM. (2019). Superinfection and cell regeneration can lead to chronic viral coinfections. Journal of theoretical biology, (466)

González-Parra G, Dobrovolny HM. (2018). Modeling of fusion inhibitor treatment of RSV in African green monkeys. Journal of theoretical biology, (456)

González-Parra G, Dobrovolny HM. (2018). A quantitative assessment of dynamical differences of RSV infections in vitro and in vivo. Virology, (523)

Melville K, Rodriguez T, Dobrovolny HM. (2018). Investigating Different Mechanisms of Action in Combination Therapy for Influenza. Frontiers in pharmacology, (9)

Deecke L, Dobrovolny HM. (2018). Intermittent treatment of severe influenza. Journal of theoretical biology, (442)

Gonzàlez-Parra G, De Ridder F, Huntjens D, Roymans D, Ispas G, Dobrovolny HM. (2018). A comparison of RSV and influenza in vitro kinetic parameters reveals differences in infecting time. PloS one, 13(2)

Pinky L, Dobrovolny HM. (2017). The impact of cell regeneration on the dynamics of viral coinfection. Chaos (Woodbury, N.Y.), 27(6)

Dobrovolny HM, Beauchemin CAA. (2017). Modelling the emergence of influenza drug resistance: The roles of surface proteins, the immune response and antiviral mechanisms. PloS one, 12(7)

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