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Li Gao

Bio

Functional genomics and molecular genetics of complex cardiopulmonary diseases, with a focus on translational studies applying fundamental genetic insight into the clinical setting.

Education

Affiliations

Preferred Pronouns

Prefer not to disclose

Personal Academic Website

Topics of Interest/Expertise
 

Countries of Work/Collaboration

United States

Projects

Papers

Zhang LY, Lu MP, Wang J, Gao L, Cheng L. (2026). Cumulative adverse childhood experiences and parent-reported allergic conditions and asthma among U.S. children: A nationally representative study. The American psychologist

Zhang LY, Wang J, Chen RX, Chen ZB, Gao L, Cheng L. (2026). Association Between Body Roundness Index and Hearing Loss: A Cross-Sectional Study of NHANES. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Le M, McCaffrey T, Gao L, Saini S. (2025). Biopredictors for Omalizumab Response in Patients with Chronic Spontaneous Urticaria. The journal of allergy and clinical immunology. In practice

Tiniakou E, Casciola-Rosen L, Thomas MA, Manabe Y, Antar AA, Damarla M, Hassoun PM, Gao L, Wang Z, Zeger S, Rosen A. (2024). Autoantibodies in hospitalised patients with COVID-19. Clinical & translational immunology, 13(12)

Gao L, Skinner J, Nath T, Lin Q, Griffiths M, Damico RL, Pauciulo MW, Nichols WC, Hassoun PM, Everett AD, Johns RA. (2024). Resistin predicts disease severity and survival in patients with pulmonary arterial hypertension. Respiratory research, 25(1)

Ding N, Nath T, Damarla M, Gao L, Hassoun PM. (2024). Early predictive values of clinical assessments for ARDS mortality: a machine-learning approach. Scientific reports, 14(1)

Gao L, Rafaels N, Dudenkov TM, Damarla M, Damico R, Maloney JP, Moss M, Martin GS, Sevransky J, Shanholtz C, Herr DL, Garcia JGN, Hernandez-Beeftink T, Villar J, Flores C, Beaty TH, Brower R, Hassoun PM, Barnes KC. (2023). Xanthine oxidoreductase gene polymorphisms are associated with high risk of sepsis and organ failure. Respiratory research, 24(1)

MacGlashan D Jr., Gao L. (2023). Association of a SYK promoter polymorphism with SYK expression and IgE-mediated histamine release. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 53(5)

Casciola-Rosen L, Thiemann DR, Andrade F, Trejo-Zambrano MI, Leonard EK, Spangler JB, Skinner NE, Bailey J, Yegnasubramanian S, Wang R, Vaghasia AM, Gupta A, Cox AL, Ray SC, Linville RM, Guo Z, Searson PC, Machamer CE, Desiderio S, Sauer LM, Laeyendecker O, Garibaldi BT, Gao L, Damarla M, Hassoun PM, Hooper JE, Mecoli CA, Christopher-Stine L, Gutierrez-Alamillo L, Yang Q, Hines D, Clarke WA, Rothman RE, Pekosz A, Fenstermacher KZ, Wang Z, Zeger SL, Rosen A. (2022). IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function. JCI insight

Yang F, Limjunyawong N, Peng Q, Schroeder JT, Saini S, MacGlashan D Jr., Dong X, Gao L. (2022). Biological screening of a unique drug library targeting MRGPRX2. Frontiers in immunology, (13)

Putcha N, Fawzy A, Matsui EC, Liu MC, Bowler RP, Woodruff PG, O'Neal WK, Comellas AP, Han MK, Dransfield MT, Wells JM, Lugogo N, Gao L, Talbot CC Jr., Hoffman EA, Cooper CB, Paulin LM, Kanner RE, Criner G, Ortega VE, Barr RG, Krishnan JA, Martinez FJ, Drummond MB, Wise RA, Diette GB, Hersh CP, Hansel NN. (2020). Clinical Phenotypes of Atopy and Asthma in COPD: A Meta-analysis of SPIROMICS and COPDGene. Chest, 158(6)

Shtessel M, Limjunyawong N, Oliver ET, Chichester K, Gao L, Dong X, Saini SS. (2020). MRGPRX2 Activation Causes Increased Skin Reactivity in Patients with Chronic Spontaneous Urticaria. The Journal of investigative dermatology

Ma Z, Qi J, Gao L, Zhang J. Role of Exercise on Alleviating Pressure Overload-Induced Left Ventricular Dysfunction and Remodeling via AMPK-Dependent Autophagy Activation. International heart journal, 61(5)

Peng X, Zhao M, Gao L, Sen R, MacGlashan D Jr.. (2020). Identifying regulatory pathways of spleen tyrosine kinase expression in human basophils. The Journal of allergy and clinical immunology, 145(3)

Ma J, Chen C, Liu Y, Damarla M, Vonakis BM, Guan X, Gao L. (2018). Altered expression of TIAM1 in endotoxin-challenged airway epithelial cells and rodent septic models. Journal of thoracic disease, 10(6)

Liu L, Zhai C, Pan Y, Zhu Y, Shi W, Wang J, Yan X, Su X, Song Y, Gao L, Li M. (2018). Sphingosine-1-phosphate induces airway smooth muscle cell proliferation, migration, and contraction by modulating Hippo signaling effector YAP. American journal of physiology. Lung cellular and molecular physiology, 315(4)

Zhu Y, Li F, Shi W, Zhai C, Wang J, Yan X, Wang Q, Zhang Q, Yang L, Gao L, Li M. (2018). COP9 signalosome subunit 6 mediates PDGF -induced pulmonary arterial smooth muscle cells proliferation. Experimental cell research, 371(2)

Damarla M, Johnston LF, Liu G, Gao L, Wang L, Varela L, Kolb TM, Kim BS, Damico RL, Hassoun PM. (2017). XOR inhibition with febuxostat accelerates pulmonary endothelial barrier recovery and improves survival in lipopolysaccharide-induced murine sepsis. Physiological reports, 5(15)

Liu L, Pan Y, Zhai C, Zhu Y, Ke R, Shi W, Wang J, Yan X, Su X, Song Y, Gao L, Li M. (2017). Activation of peroxisome proliferation-activated receptor-γ inhibits transforming growth factor-β1-induced airway smooth muscle cell proliferation by suppressing Smad-miR-21 signaling. Journal of cellular physiology, 234(1)

Zhang LQ, Van Haandel L, Xiong M, Huang P, Heruth DP, Bi C, Gaedigk R, Jiang X, Li DY, Wyckoff G, Grigoryev DN, Gao L, Li L, Wu M, Leeder JS, Ye SQ. (2017). Metabolic and molecular insights into an essential role of nicotinamide phosphoribosyltransferase. Cell death & disease, 8(3)

Ke R, Xie X, Li S, Pan Y, Wang J, Yan X, Zang W, Gao L, Li M. (2017). 5-HT induces PPAR γ reduction and proliferation of pulmonary artery smooth muscle cells via modulating GSK-3β/β-catenin pathway. Oncotarget, 8(42)

Liu Q, Li D, Berger AE, Johns RA, Gao L. (2017). Survival and prognostic factors in hypertrophic cardiomyopathy: a meta-analysis. Scientific reports, 7(1)

Li S, Pan Y, Ke R, Xie X, Zhai C, Shi W, Wang J, Yan X, Chai L, Wang Q, Zhang Q, Su X, Yang L, Gao L, Li M. (2017). Inhibition of phosphodiesterase-5 suppresses calcineurin/NFAT- mediated TRPC6 expression in pulmonary artery smooth muscle cells. Scientific reports, 7(1)

Zhu Y, Wu Y, Shi W, Wang J, Yan X, Wang Q, Liu Y, Yang L, Gao L, Li M. (2017). Inhibition of ubiquitin proteasome function prevents monocrotaline-induced pulmonary arterial remodeling. Life sciences, (173)

Long X, Daya M, Zhao J, Rafaels N, Liang H, Potee J, Campbell M, Zhang B, Araujo MI, Oliveira RR, Mathias RA, Gao L, Ruczinski I, Georas SN, Vercelli D, Beaty TH, Barnes KC, Chen X, Chen Q. (2017). The role of ST2 and ST2 genetic variants in schistosomiasis. The Journal of allergy and clinical immunology, 140(5)

Xie X, Li S, Zhu Y, Liu L, Pan Y, Wang J, Shi W, Song Y, Yang L, Gao L, Zang W, Li M. (2017). MicroRNA-27a/b mediates endothelin-1-induced PPARγ reduction and proliferation of pulmonary artery smooth muscle cells. Cell and tissue research, 369(3)

Xie X, Li S, Zhu Y, Liu L, Ke R, Wang J, Yan X, Yang L, Gao L, Zang W, Li M. (2018). Egr-1 mediates leptin-induced PPARγ reduction and proliferation of pulmonary artery smooth muscle cells. Molecular biology of the cell, 29(3)

Ke R, Liu L, Zhu Y, Li S, Xie X, Li F, Song Y, Yang L, Gao L, Li M. (2016). Knockdown of AMPKα2 Promotes Pulmonary Arterial Smooth Muscle Cells Proliferation via mTOR/Skp2/p27(Kip1) Signaling Pathway. International journal of molecular sciences, 17(6)

Liu L, Pan Y, Song Y, Su X, Ke R, Yang L, Gao L, Li M. (2016). Activation of AMPK α2 inhibits airway smooth muscle cells proliferation. European journal of pharmacology, (791)

Wu D, Talbot CC Jr., Liu Q, Jing ZC, Damico RL, Tuder R, Barnes KC, Hassoun PM, Gao L. (2016). Identifying microRNAs targeting Wnt/β-catenin pathway in end-stage idiopathic pulmonary arterial hypertension. Journal of molecular medicine (Berlin, Germany), 94(8)

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