I earned my BS in Environmental Engineering from Wilkes University in 2004, specializing in water treatment and hydraulics. Through international contracting and domestic consulting work I recognized the need to advance the understanding of health protection and cultural appropraitness of engineering technologies. Through this interest I sought out the mentorship of Dr. Charles N. Haas, and in doing so, earned my Ph.D. in Environmental Engineering from Drexel University in 2009. My dissertation was focused on counter bioterror research, particularly and advanced dose response for inahaltion anthrax. Under Dr. Haas' mentorship I learned risk modeling methods, dose response modeling, and improved my engineering modeling and analysis skills. For my post-doctoral research I sought out Dr. Joan B. Rose at Michigan State University. Here I further developed my risk modeling and health analytics skills. I re-engaged in my first professional passion - water research. Through work with Chuck and Joan, I developed my international reputation in risk modeling and analyses of engineered and natural systems.
National Science Foundation, Engineering (ENG)
People: Mark Weir
2022 – 2025 Continue Reading Collaborative Research: An integrative framework for decision support models including plumbing system dynamics and value of information to meet Legionella control goals
Joshi S, Quon H, Shen Y, Raskin L, Weir MH, Singh R, Gurian PL, Hamilton KA. (2025). A quantitative microbial risk assessment (QMRA) approach to determine water quality guidelines for Mycobacterium avium complex (MAC) in building plumbing. Water research, (285)
Kozak S, Roiko A, Gutjahr-Holland K, Ahmed W, Veal C, Fisher P, Toze S, Weir M, Stratton H. (2025). The use of faecal indicator organisms to manage microbial health risks in recreational waterways not impacted by point sources of sewage: a systematic review of the epidemiological evidence. Journal of water and health, 23(5)
Hamilton KA, Ciol Harrison J, Mitchell J, Weir M, Verhougstraete M, Haas CN, Nejadhashemi AP, Libarkin J, Gim Aw T, Bibby K, Bivins A, Brown J, Dean K, Dunbar G, Eisenberg JNS, Emelko M, Gerrity D, Gurian PL, Hartnett E, Jahne M, Jones RM, Julian TR, Li H, Li Y, Gibson JM, Medema G, Meschke JS, Mraz A, Murphy H, Oryang D, Owusu-Ansah EDJ, Pasek E, Pradhan AK, Razzolini MTP, Ryan MO, Schoen M, Smeets PWMH, Soller J, Solo-Gabriele H, Williams C, Wilson AM, Zimmer-Faust A, Alja'fari J, Rose JB. (2024). Research gaps and priorities for quantitative microbial risk assessment (QMRA). Risk analysis : an official publication of the Society for Risk Analysis
Mitchell J, Li H, Weir MH, Libarkin J, Pasek E. (2024). Development and evaluation of an intensive short course: the Quantitative Microbial Risk Assessment Interdisciplinary Instructional Institute (QMRA III). Journal of microbiology & biology education
Verhougstraete M, Cooksey E, Walker JP, Wilson AM, Lewis MS, Yoder A, Elizondo-Craig G, Almoslem M, Forysiak E, Weir MH. (2024). Impact of terminal cleaning in rooms previously occupied by patients with healthcare-associated infections. PloS one, 19(7)
Ma D, Weir MH, Hull NM. (2023). Fluence-based QMRA model for bacterial photorepair and regrowth in drinking water after decentralized UV disinfection. Water research, (231)
Li X, Xu J, Wu J, Weir MH, Xi C. (2023). Prevalence of Legionella in a Public Building Water Plumbing System During COVID-19 Lockdown. Environment & health (Washington, D.C.), 1(5)
KhudaBukhsh WR, Bastian CD, Wascher M, Klaus C, Sahai SY, Weir MH, Kenah E, Root E, Tien JH, Rempała GA. (2023). Projecting COVID-19 cases and hospital burden in Ohio. Journal of theoretical biology, (561)
KhudaBukhsh WR, Bastian CD, Wascher M, Klaus C, Sahai SY, Weir M, Kenah E, Root E, Tien JH, Rempala G. (2022). Projecting COVID-19 Cases and Subsequent Hospital Burden in Ohio. medRxiv : the preprint server for health sciences
Mraz AL, Weir MH. (2022). Knowledge to Predict Pathogens: Legionella pneumophila Lifecycle Systematic Review Part II Growth within and Egress from a Host Cell. Microorganisms, 10(1)
Lu E, Ai Y, Davis A, Straathof J, Halloran K, Hull N, Winston R, Weir MH, Soller J, Bohrerova Z, Oglesbee M, Lee J. (2022). Wastewater surveillance of SARS-CoV-2 in dormitories as a part of comprehensive university campus COVID-19 monitoring. Environmental research
Noh Y, Shannahan JH, Hoover AG, Pennell KG, Weir MH, Whelton AJ. (2022). Bystander chemical exposures and injuries associated with nearby plastic sewer pipe manufacture: public health practice and lessons. Journal of environmental health, 85(4)
King MF, Wilson AM, Weir MH, López-García M, Proctor J, Hiwar W, Khan A, Fletcher LA, Sleigh PA, Clifton I, Dancer SJ, Wilcox M, Reynolds KA, Noakes CJ. (2021). Modeling fomite-mediated SARS-CoV-2 exposure through personal protective equipment doffing in a hospital environment. Indoor air
Wilson AM, Jones RM, Lugo Lerma V, Abney SE, King MF, Weir MH, Sexton JD, Noakes CJ, Reynolds KA. (2021). Respirators, face masks, and their risk reductions via multiple transmission routes for first responders within an ambulance. Journal of occupational and environmental hygiene
Wilson AM, Weir MH, King MF, Jones RM. (2021). Comparing approaches for modelling indirect contact transmission of infectious diseases. Journal of the Royal Society, Interface, 18(182)
Weir MH, Wood TA, Zimmer-Faust A. (2020). Development of methods to estimate microcystins removal and water treatment resiliency using mechanistic risk modelling. Water research, (190)
Wilson AM, Weir MH, Bloomfield SF, Scott EA, Reynolds KA. (2020). Modeling COVID-19 infection risks for a single hand-to-fomite scenario and potential risk reductions offered by surface disinfection. American journal of infection control
Gonzalez R, Curtis K, Bivins A, Bibby K, Weir MH, Yetka K, Thompson H, Keeling D, Mitchell J, Gonzalez D. (2020). COVID-19 surveillance in Southeastern Virginia using wastewater-based epidemiology. Water research, (186)
Wilson AM, King MF, López-García M, Weir MH, Sexton JD, Canales RA, Kostov GE, Julian TR, Noakes CJ, Reynolds KA. (2020). Evaluating a transfer gradient assumption in a fomite-mediated microbial transmission model using an experimental and Bayesian approach. Journal of the Royal Society, Interface, 17(167)
Dean K, Weir MH, Mitchell J. (2019). Development of a dose-response model for Naegleria fowleri. Journal of Water and Health, 17(1)
Alexis L Mraz, Sharon Nappier, Charles N Haas, Mark H Weir. (2019). Dose response models for Eastern US, Western US and Venezuelan equine encephalitis viruses in micePart I: Standard dose response model and inference of host age. Microbial Risk Analysis, (14)
Mark H Weir. (2019). A data simulation method to optimize a mechanistic dose-response model for viral loads of hepatitis A. Microbial Risk Analysis
Mark H Weir, Alexis L Mraz, Jade Mitchell. (2019). An Advanced Risk Modeling Method to Estimate Legionellosis Risks Within a Diverse Population. Water, 12(1)
Adhikari U, Chabrelie A, Weir M, Boehnke K, McKenzie E, Ikner L, Wang M, Wang Q, Young K, Haas CN, Rose J, Mitchell J. (2019). A Case Study Evaluating the Risk of Infection from Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV) in a Hospital Setting Through Bioaerosols. Risk analysis : an official publication of the Society for Risk Analysis, 39(12)
Madera-García V, Mraz AL, López-Gálvez N, Weir MH, Werner J, Beamer PI, Verhougstraete MP. (2019). Legionella pneumophila as a Health Hazard to Miners: A Pilot Study of Water Quality and QMRA. Water, 11(8)
Hamilton KA, Chen A, de-Graft Johnson E, Gitter A, Kozak S, Niquice C, Zimmer-Faust AG, Weir MH, Mitchell J, Gurian P. (2018). Salmonella risks due to consumption of aquaculture-produced shrimp. Microbial Risk Analysis, (9)
Weir MH, Mraz AL, Nappier S, Haas CN. (2018). Dose-Response Models for Eastern US, Western US and Venezuelan Equine Encephalitis Viruses in Mice - Part II: Quantification of the Effects of Host Age on the Dose Response. Microbial Risk Analysis, (9)
Alexis L Mraz, Mark H Weir. (2018). Knowledge to predict pathogens: Legionella pneumophila lifecycle critical review part I uptake into host cells. Water, 10(2)
Bope A, Weir MH, Pruden A, Morowitz M, Mitchell J, Dannemiller KC. (2018). Translating research to policy at the NCSE 2017 symposium "Microbiology of the Built Environment: Implications for Health and Design". Microbiome, 6(1)
Canales RA, Reynolds KA, Wilson AM, Fankem SLM, Weir MH, Rose JB, Abd-Elmaksoud S, Gerba CP. (2018). Modeling the role of fomites in a norovirus outbreak. Journal of Occupational and Environmental Hygiene, 16(1)
Alexis Mraz, Mark Weir, Patrick McLaughlin. (2017). Efficacy of anuran trapping and monitoring techniques in the tropical forests of Bioko Island, Equatorial Guinea. Amphibia-Reptilia, 39(4)
Brouwer AF, Weir MH, Eisenberg MC, Meza R, Eisenberg JNS. (2017). Dose-response relationships for environmentally mediated infectious disease transmission models. PLoS computational biology, 13(4)
Rosen MB, Pokhrel LR, Weir MH. (2017). A discussion about public health, lead and Legionella pneumophila in drinking water supplies in the United States. The Science of the total environment, (590-591)
Lok R Pokhrel, Nicholas Ettore, Zachary L Jacobs, Asha Zarr, Mark H Weir, Phillip R Scheuerman, Sushil R Kanel, Brajesh Dubey. (2016). Novel carbon nanotube (CNT)-based ultrasensitive sensors for trace mercury (II) detection in water: A review. Science of The Total Environment, (574)
Mark H Weir, Tomoyuki Shibata, Yoshifumi Masago, Dena L Cologgi, Joan B Rose. (2016). Effect of surface sampling and recovery of viruses and non-spore-forming bacteria on a Quantitative Microbial Risk Assessment model for fomites. Environmental Science & Technology, 50(11)
Hamilton KA, Weir MH, Haas CN. (2017). Dose response models and a quantitative microbial risk assessment framework for the Mycobacterium avium complex that account for recent developments in molecular biology, taxonomy, and epidemiology. Water Research, (109)
Mark H Weir. (2015). Dose-Response Modeling and Use: Challenges and Uncertainties in Environmental Exposure. Manual of Environmental Microbiology
María Soledad Rodriguez-Alvarez, Mark H Weir, Joanna M Pope, Lucas Seghezzo, Verónica B Rajal, María Mónica Salusso, Liliana B Morana. (2015). Development of a relative risk model for drinking water regulation and design recommendations for a peri urban region of Argentina. International Journal of Hygiene and Environmental Health, 218(7)
Kirk J Breuninger, Mark H Weir. (2015). Development of an Interspecies Nested Dose‐Response Model for Mycobacterium avium subspecies paratuberculosis. Risk Analysis: An International Journal, 35(8)
Sondra S Teske, Mark H Weir, Timothy A Bartrand, Yin Huang, Sushil B Tamrakar, Charles N Haas. (2013). Dose-Response Models Incorporating Aerosol Size Dependency for Francisella tularensis. Risk Analysis: An International Journal, 34(5)
Thomas Walski, William Bezts, Emanuel T Posluszny, Mark Weir, Brian Whitman. (2012). Understanding the Hydraulics of Water Distribution System Leaks. Critical Transitions in Water and Environmental Resources Management
Sondra S Teske, Yin Huang, Sushil B Tamrakar, Timothy A Bartrand, Mark H Weir, Charles N Haas. (2011). Animal and Human Dose-Response Models for Brucella Species. Risk Analysis: An International Journal, 31(10)
Mark H Weir, Maria Tereza Pepe Razzolini, Joan B Rose, Yoshifumi Masago. (2011). Water reclamation redesign for reducing Cryptosporidium risks at a recreational spray park using stochastic models. Water Research, 45(19)
Mark H Weir, Charles N Haas. (2011). A Model for In-vivo Delivered Dose Estimation for Inhaled Bacillus anthracis Spores in Humans with Interspecies Extrapolation. Environmental Science & Technology, 45(13)
Maria Tereza Pepe Razzolini, Mark H Weir, Maria Helena Matte, Glavur Rogerio Matte, Licia Natal Fernandes, Joan B Rose. (2011). Risk of Giardia infection for drinking water and bathing in a peri-urban area in São Paulo, Brazil. International Journal of Environmental Health Research, 21(3)
Toru Watanabe, Timothy A Bartrand, Mark H Weir, Tatsuo Omura, Charles N Haas. (2010). Development of a dose-response model for SARS coronavirus. Risk Analysis: An International Journal, 30(7)
Mark H Weir, Charles N Haas. (2009). Quantification of the Effects of Age on the Dose Response of Variola major in Suckling Mice. Human and Ecological Risk Assessment: An International Journal, 15(6)
Timothy A Bartrand, Mark H Weir, Charles N Haas. (2008). Dose-Response Models for Inhalation of Bacillus anthracis Spores: Interspecies Comparisons. Risk Analysis: An International Journal, 28(4)
Timothy A Bartrand, Mark Weir, Charles N Haas. (2007). Advancing the quality of drinking water: Expert workshop to formulate a research agenda. Environmental Engineering Science, 24(7)
Thomas Walski, William Bezts, Emanuel T Posluszny, Mark Weir, Brian E Whitman. (2006). Modeling leakage reduction through pressure control. Journal of American Water Works Association, 98(4)
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