I work at the intersection of mathematical modeling, immunology and infectious diseases. I did my PhD at Princeton University, where I modeled the dynamics of acute infections at both the population and within-host levels. One particular focus was investigating the impact of immune life-histories on epidemiological dynamics of common pathogens such as measles and influenza. In my current postdoc at Columbia University, I am delving deeper into within-host viral dynamics and the generation of immune memory. Recent projects span a number of pathogens including HIV, influenza, and SARS-CoV-2. Ultimately, I am interested in understanding how fine-scale immunological responses modulate long-term population dynamics. I am also interested in creating useful tools for reproducing and disseminating research findings. These include R packages, shiny apps, and software tutorials.
She/her/hers
United States
United Kingdom
Morris SE, O'Halloran A, Sundaresan D, Olson SM, Chung JR, Ellington S, Bozio CH, Iuliano AD, Biggerstaff M, Reed C. (2026). Public health benefits of maternal influenza vaccination among pregnant women and infants <6 months in the United States, 2011-2020. Vaccine, (89)
Couture A, Biggerstaff M, Sheppard M, Budd A, Kite-Powell A, Morris SE. (2026). Spatiotemporal transmission of influenza in the US during the 2022/23 season. Epidemics, (54)
Chan LYH, Morris SE, Stockwell MS, Bowman NM, Asturias E, Rao S, Lutrick K, Ellingson KD, Nguyen HQ, Maldonado Y, McLaren SH, Sano E, Biddle JE, Smith-Jeffcoat SE, Biggerstaff M, Rolfes MA, Talbot HK, Grijalva CG, Borchering RK, Mellis AM, . (2026). Estimating the generation time for SARS-CoV-2 transmission using United States household data, December 2021-May 2023. Scientific reports
Chan LYH, Morris S, Hassell N, Marcenac P, Couture A, Colon A, Kniss K, Budd A, Biggerstaff M, Borchering R. (2026). Understanding spatiotemporal clustering of seasonal influenza in the United States. BMC infectious diseases
Chan LYH, Morris SE, Stockwell MS, Bowman NM, Asturias E, Rao S, Lutrick K, Ellingson KD, Nguyen HQ, Maldonado Y, McLaren SH, Sano E, Biddle JE, Smith-Jeffcoat SE, Biggerstaff M, Rolfes MA, Talbot HK, Grijalva CG, Borchering RK, Mellis AM, . (2025). Estimating the generation time for influenza transmission using household data in the United States. Epidemics, (50)
Morris SE, Mathis SM, Reeves E, Chung JR, Borchering RK, Lewis NM, Masalovich S, Garg S, Uyeki TM, Iuliano AD, Tenforde MW, Reed C, Biggerstaff M. (2025). Modeling the Potential Impacts of Outpatient Antiviral Treatment in Reducing Influenza-Associated Hospitalizations in the United States. The Journal of infectious diseases
Morris SE, O'Halloran A, Sundaresan D, Dawood FS, Ellington S, Grohskopf LA, Olson SM, Borchering RK, Bozio CH, Reed C, Biggerstaff M. (2025). Heterogeneity in seasonal influenza vaccination opportunity and disease risk during pregnancy and in infants <6 months. Vaccine, (68)
Morris SE, Mathis SM, Chung JR, Flannery B, O'Halloran A, Bozio CH, Lu PJ, Santibanez TA, Daly P, Merced-Morales A, Kniss K, Budd A, Grohskopf LA, Reed C, Biggerstaff M, Iuliano AD. (2025). Estimating historical impacts of vaccination against influenza B/Yamagata in the United States to inform possible risks of re-emergence in the absence of vaccination. Vaccine: X, (26)
Morris SE, Mathis SM, Chung JR, Flannery B, O'Halloran A, Cummings CN, Garg S, Lu PJ, Santibanez TA, Reed C, Biggerstaff M, Iuliano AD. (2025). Estimating historical disease burden and the impact of vaccination by influenza type and subtype in the United States, 2016-2020. Vaccine: X, (26)
Morris SE, Nguyen HQ, Grijalva CG, Hanson KE, Zhu Y, Biddle JE, Meece JK, Halasa NB, Chappell JD, Mellis AM, Reed C, Biggerstaff M, Belongia EA, Talbot HK, Rolfes MA. (2024). Influenza virus shedding and symptoms: Dynamics and implications from a multiseason household transmission study. PNAS nexus, 3(9)
Saad-Roy CM, Morris SE, Boots M, Baker RE, Lewis BL, Farrar J, Marathe MV, Graham AL, Levin SA, Wagner CE, Metcalf CJE, Grenfell BT. (2024). Impact of waning immunity against SARS-CoV-2 severity exacerbated by vaccine hesitancy. PLoS computational biology, 20(8)
Morris SE, Gilmer M, Threlkel R, Brammer L, Budd AP, Iuliano AD, Reed C, Biggerstaff M. (2024). Detection of Novel Influenza Viruses Through Community and Healthcare Testing: Implications for Surveillance Efforts in the United States. Influenza and other respiratory viruses, 18(5)
Montgomery MP, Morris SE, Rolfes MA, Kittikraisak W, Samuels AM, Biggerstaff M, Davis WW, Reed C, Olsen SJ. (2023). The role of asymptomatic infections in influenza transmission: what do we really know. The Lancet. Infectious diseases
Morris SE, Zipfel CM, Peer K, Madewell ZJ, Brenner S, Garg S, Paul P, Slayton RB, Biggerstaff M. (2023). Modeling the impacts of antiviral prophylaxis strategies in mitigating seasonal influenza outbreaks in nursing homes. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Saad-Roy CM, Morris SE, Metcalf CJE, Mina MJ, Baker RE, Farrar J, Holmes EC, Pybus OG, Graham AL, Levin SA, Grenfell BT, Wagner CE. (2021). Partial immunity and SARS-CoV-2 mutations-Response. Science (New York, N.Y.), 372(6540)
Wagner CE, Saad-Roy CM, Morris SE, Baker RE, Mina MJ, Farrar J, Holmes EC, Pybus OG, Graham AL, Emanuel EJ, Levin SA, Metcalf CJE, Grenfell BT. (2021). Vaccine nationalism and the dynamics and control of SARS-CoV-2. Science (New York, N.Y.)
Szabo PA, Dogra P, Gray JI, Wells SB, Connors TJ, Weisberg SP, Krupska I, Matsumoto R, Poon MML, Idzikowski E, Morris SE, Pasin C, Yates AJ, Ku A, Chait M, Davis-Porada J, Guo XV, Zhou J, Steinle M, Mackay S, Saqi A, Baldwin MR, Sims PA, Farber DL. (2021). Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19. Immunity
Saad-Roy CM, Morris SE, Metcalf CJE, Mina MJ, Baker RE, Farrar J, Holmes EC, Pybus OG, Graham AL, Levin SA, Grenfell BT, Wagner CE. (2021). Epidemiological and evolutionary considerations of SARS-CoV-2 vaccine dosing regimes. Science (New York, N.Y.)
Morris SE, Dziobek-Garrett L, Strehlau R, Schröter J, Shiau S, Anelone AJN, Paximadis M, de Boer RJ, Abrams EJ, Tiemessen CT, Kuhn L, Yates AJ. (2020). Quantifying the Dynamics of HIV Decline in Perinatally Infected Neonates on Antiretroviral Therapy. Journal of acquired immune deficiency syndromes (1999), 85(2)
Saad-Roy CM, Wagner CE, Baker RE, Morris SE, Farrar J, Graham AL, Levin SA, Mina MJ, Metcalf CJE, Grenfell BT. (2020). Immune life history, vaccination, and the dynamics of SARS-CoV-2 over the next 5 years. Science (New York, N.Y.)
Morris SE, Dziobek-Garrett L, Yates AJ, Collaboration With The Epiical Consortium I. (2020). ushr: Understanding suppression of HIV in R. BMC bioinformatics, 21(1)
Morris SE, Farber DL, Yates AJ. (2019). Tissue-Resident Memory T Cells in Mice and Humans: Towards a Quantitative Ecology. Journal of immunology (Baltimore, Md. : 1950), 203(10)
Morris SE, Yates AJ, de Swart RL, de Vries RD, Mina MJ, Nelson AN, Lin WW, Kouyos RD, Griffin DE, Grenfell BT. (2018). Modeling the measles paradox reveals the importance of cellular immunity in regulating viral clearance. PLoS pathogens, 14(12)
Morris SE, Freiesleben de Blasio B, Viboud C, Wesolowski A, Bjørnstad ON, Grenfell BT. (2018). Analysis of multi-level spatial data reveals strong synchrony in seasonal influenza epidemics across Norway, Sweden, and Denmark. PloS one, 13(5)
Morris SE, Pitzer VE, Viboud C, Metcalf CJ, Bjørnstad ON, Grenfell BT. (2015). Demographic buffering: titrating the effects of birth rate and imperfect immunity on epidemic dynamics. Journal of the Royal Society, Interface, 12(104)
Morris SE, Zelner JL, Fauquier DA, Rowles TK, Rosel PE, Gulland F, Grenfell BT.. (2015). Partially observed epidemics in wildlife hosts: modelling an outbreak of dolphin morbillivirus in the northwestern Atlantic. J R Soc Interface, 12(112)
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