
REAL-TIME TRACKING OF VIRUS EVOLUTION FOR VACCINE STRAIN SELECTION AND EPIDEMIOLOGICAL INVESTIGATION
National Institutes of Health, National Institute of General Medical Sciences
People: Trevor Bedford
2016 – 2021
Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center
Department of Epidemiology, School of Public Health, University of Washington
Computational Biology Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center
Genome Sciences, University of Washington
Bedford Lab, Fred Hutchinson Cancer Research Center
National Institutes of Health, National Institute of General Medical Sciences
People: Trevor Bedford
2016 – 2021
National Institutes of Health, National Institute of General Medical Sciences
People: Trevor Bedford, John Huddleston, M Halloran
2014 – 2020
Dudas G, Carvalho LM, Rambaut A, Bedford T. (2018). MERS-CoV spillover at the camel-human interface. eLife
Neher RA, Bedford T. (2018). Real-Time Analysis and Visualization of Pathogen Sequence Data. Journal of Clinical Microbiology, 56(11)
Bell SM, Bedford T. (2017). Modern-day SIV viral diversity generated by extensive recombination and cross-species transmission. PLoS Pathogens, 13(7)
Bedford T, Malik HS. (2016). Did a Single Amino Acid Change Make Ebola Virus More Virulent. Cell, 167(4)
Bedford T, Riley S, Barr IG, Broor S, Chadha M, Cox NJ, Daniels RS, Gunasekaran CP, Hurt AC, Kelso A, Klimov A, Lewis NS, Li X, McCauley JW, Odagiri T, Potdar V, Rambaut A, Shu Y, Skepner E, Smith DJ, Suchard MA, Tashiro M, Wang D, Xu X, Lemey P, Russell CA. (2015). Global circulation patterns of seasonal influenza viruses vary with antigenic drift. Nature, 523(7559)
Neher RA, Bedford T. (2015). nextflu: real-time tracking of seasonal influenza virus evolution in humans. Bioinformatics (Oxford, England), 31(21)
Frost SD, Pybus OG, Gog JR, Viboud C, Bonhoeffer S, Bedford T. (2015). Eight challenges in phylodynamic inference. Epidemics
Bedford T, Suchard MA, Lemey P, Dudas G, Gregory V, Hay AJ, McCauley JW, Russell CA, Smith DJ, Rambaut A. (2014). Integrating influenza antigenic dynamics with molecular evolution. Elife
Landis MJ, Bedford T. (2014). Phylowood: interactive web-based animations of biogeographic and phylogeographic histories. Bioinformatics (Oxford, England), 30(1)
Volz EM, Koelle K, Bedford T. (2013). Viral phylodynamics. PLoS computational biology, 9(3)
Bedford T, Rambaut A, Pascual M. (2012). Canalization of the evolutionary trajectory of the human influenza virus. BMC biology
Bedford T, Cobey S, Pascual M. (2011). Strength and tempo of selection revealed in viral gene genealogies. BMC evolutionary biology
Bedford T, Cobey S, Beerli P, Pascual M. (2010). Global migration dynamics underlie evolution and persistence of human influenza A (H3N2). PLoS pathogens, 6(5)
Bedford T, Hartl DL. (2009). Optimization of gene expression by natural selection. Proceedings of the National Academy of Sciences of the United States of America, 106(4)
Bedford T, Hartl DL. (2008). Overdispersion of the molecular clock: temporal variation of gene-specific substitution rates in Drosophila. Molecular biology and evolution, 25(8)
Bedford T, Wapinski I, Hartl DL. (2008). Overdispersion of the molecular clock varies between yeast, Drosophila and mammals. Genetics, 179(2)
MIDAS Coordination Center
University of Pittsburgh
A737 Public Health
130 DeSoto Street
Pittsburgh PA 15261