Community-Oriented Action, Science and Translation Superfund Center (COAST)

PROJECT SUMMARY: DATA MANAGEMENT AND ANALYSIS CORE (DMAC) Partnering with COAST Cores and Research Projects that define and apply (Community Engagement Core, CEC), innovate (Research Projects), operationalize (Research Projects and Analytical Chemistry Core, ACC), and coordinate, translate, and evaluate (Administrative Core), the Data Management and Analysis Core (DMAC) functions to enable and interpret translational environmental health-related research. Specifically, the DMAC will: 1) Develop and support data pipelines linking the wide range of COAST low- and high- dimensional datasets and their meta-data and integrate data across all projects (Aim 1); 2) Advance expanded and customized data management and analysis plans, implement novel analytic approaches, and expand the COAST data and analytic infrastructure to research translation (Aim 2); and 3) Enable seamless integration and interoperability of data across different centers and projects while ensuring data reusability and fidelity (Aim 3). All three functions are essential to create, curate, analyze, and translate environmental health-related data of different measurement types taken from different places at different times into informative, interpretable, and communicable results for community investigators, stakeholders, researchers, and policy makers. Building on a connected collaborative network between our experienced data science professionals in Emory’s P30 Exposome Center, P50 Translational Center, the Georgia Clinical & Translational Science Alliance, and community partners, the DMAC will 1) provide the Administrative Core with insight into existing and emerging trends in data management and analysis from inside and outside the COAST community in order to assure training of all Investigators and support for new and early career investigators; 2) collaborate directly with the CEC in working with COAST community partners to identify relevant existing data sources, partnerships with COAST investigators, and/or support citizen science efforts to provide data collection, data management, and data communication plans; 3) partner with the ACC and the Research Projects to link health outcomes and exposure in innovative ways quantifying, operationalizing, and interpreting data within translational environmental health research; 4) develop strategies to share data across platforms within and outside COAST. Taken together, the DMAC provides clear connections to all elements of COAST and complements the Admin Core, and the other Research Projects through close collaboration in our overall theme of advancing public health and climate resilience in coastal communities by addressing the problems of hazardous substances and environmental injustice.