Through this funding opportunity announcement, we aim to encourage new and unique projects and collaborations bridging across biological scales that 1) address fundamental gaps in our mechanistic understanding of immune-related health and disease and 2) provide in silico laboratories evaluating prophylactic and therapeutic interventions.
Due by
Jan. 31, 2026, 5:00 p.m. EST.
The full RFP is available as the 2025 MISM Pilot Award RFP (opens PDF). Application submission instructions are below.
Letter of Intent
A Letter of Intent (LOI) is required to submit a MISM Pilot Grant. LOIs are mandatory and will be used to determine appropriateness for the RFA, provide feedback to submitters, aid the recruitment of appropriately knowledgeable reviewers, and for other review planning. LOIs are due Dec. 15, 2025, 5:00 p.m. EST, and should include the following information:
- Name and email of the Principal Investigator(s)
- Names of other key personnel and Institution/Department/Division Affiliation
- Descriptive title of proposed research
- Abstract (less than 350 words) describing hypotheses and aims
- LOIs should be emailed to MISM@duke.edu
How to Apply
MISM uses the MyResearchProposal online application software to submit completed applications.
- To apply, visit the Duke MyResearchProposal portal and click on “Create New Account” (or log in if you already have an account). Proposals must be submitted under the Primary Applicant’s name.
- A step-by-step user’s guide for applying via the MyResearchProposal software is available in the MyResearchProposal Application Instructions (opens PDF).
- Enter Access Code ‘MISM’ in the search box in the upper right-hand corner, scroll down the page, select the “MISM Pilot Award 2025,” and follow the instructions.
- For questions about MyResearchProposal passwords or system issues, contact myresearchproposal@duke.edu.
