CMDS had statistically significantly greater predictive and discriminative ability than EOSS for persons aged 40 to 75. While the clinical relevance of these differences is unknown, CMDS may have greater clinical utility given that it uses fewer items to risk stratify. The clinical relevance and utility need to be studied further.
and C-statistics. Median years of life lost were also computed for each score.
), and 0.02 (0.01-0.02) (C-statistics). The median years of life lost for EOSS scores 2 and 3 (low to high risk) for a reference person were 1.19 and 6.76 years. Those for CMDS scores 1, 2, 3, and 4 (low to high risk) were 1.53, 2.90, 3.91, and 8.51 years. Consistent results from the in-sample estimates were observed.
Differences in discriminative and predictive ability for all-cause mortality of two clinical staging systems, the Edmonton Obesity Staging System (EOSS) and Cardiometabolic Disease Staging (CMDS), were estimated.
Ejima K, Xavier NA, Mehta T. (2020). Comparing the Ability of Two Comprehensive Clinical Staging Systems to Predict Mortality: EOSS and CMDS. Obesity (Silver Spring, Md.), 28(2)