Ludy Carmola
Program coordinator/Research scientist
University of Georgia Continue Reading Ludy Carmola
MIDAS Network Member
Paper Information
Title
Subgenomic RNA Abundance Relative to Total Viral RNA Among Severe Acute Respiratory Syndrome Coronavirus 2 Variants.
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) subgenomic RNA (sgRNA) may indicate actively replicating virus, but sgRNA abundance has not been systematically compared between SARS-CoV-2 variants. sgRNA was quantified in 169 clinical samples by real-time reverse-transcription polymerase chain reaction, demonstrating similar relative abundance among known variants. Thus, sgRNA detection can identify individuals with active viral replication regardless of variant.
Journal
Open forum infectious diseases
Citation
Su M, Ping S, Nguyen PV, Rojas A, Hussaini L, Carmola LR, Taz A, Sullivan J, Martin GS, Piantadosi A, Martinez M, Lam WA, Anderson EJ, Waggoner JJ. (2022). Subgenomic RNA Abundance Relative to Total Viral RNA Among Severe Acute Respiratory Syndrome Coronavirus 2 Variants. Open forum infectious diseases, 9(11)
MIDAS Authors