John Huddleston
PhD Student
University of Washington Continue Reading John Huddleston
MIDAS Network Member
Paper Information
Title
The evolution and population diversity of human-specific segmental duplications.
Abstract
) where copy number never returns to the ancestral state, there is evidence of mRNA splicing, and no common gene-disruptive mutations are observed in the general population. Such duplicates are candidates for the evolution of human-specific adaptive traits.
Journal
Nature ecology & evolution
Citation
Dennis MY, Harshman L, Nelson BJ, Penn O, Cantsilieris S, Huddleston J, Antonacci F, Penewit K, Denman L, Raja A, Baker C, Mark K, Malig M, Janke N, Espinoza C, Stessman HAF, Nuttle X, Hoekzema K, Lindsay-Graves TA, Wilson RK, Eichler EE. (2017). The evolution and population diversity of human-specific segmental duplications. Nature ecology & evolution, 1(3)
MIDAS Authors