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Reza Yaesoubi

Bio

Reza Yaesoubi, PhD, is an Associate Professor at the Philip R. Lee Institute for Health Policy Studies and the Department of Epidemiology and Biostatistics at the University of California, San Francisco. He is a health decision scientist whose research focuses on developing and applying analytical methods to inform data-driven and value-based decisions in clinical care, public health, and global health. His primary area of expertise lies in guiding decisions when evidence and data evolve too rapidly for static policies or guidelines to suffice—for example, during outbreaks of novel pathogens or the spread of antimicrobial resistance. He is also interested in advancing the theoretical and methodological foundations of adaptive decision-making and health care resource allocation.

Education

Affiliations

Preferred Pronouns

He/him/his

Personal Academic Website

https://yaesoubilab.ucsf.edu/

Topics of Interest/Expertise
 

Countries of Work/Collaboration

United States
South Africa

Projects

Papers

Ekanayake-Weber MS, Rönn MM, Yin X, Hsu K, Li Y, Gift TL, Chesson H, Frankson R, Salomon JA, Grad YH, Yaesoubi R. (2026). Measuring the health benefits and costs of antimicrobial-resistant gonorrhea surveillance in the United States: an agent-based model and cost-effectiveness analysis. Lancet regional health. Americas, (62)

Murray-Watson RE, Ekanayake-Weber M, Cohen T, Hanmer J, Yaesoubi R. (2026). Acceptability of Nonpharmaceutical Interventions to Prevent the Risk of COVID-19 Infection in the United States. MDM policy & practice, 11(1)

Mikdashi F, Murray-Watson RE, Lopes R, Bilinski A, Yaesoubi R. (2026). Estimating the Quality-Adjusted Life-Year Loss due to Fatal and Nonfatal COVID-19 Outcomes across US States and Counties, July 2020 to December 2022. MDM policy & practice, 11(2)

Alves-Maciel B, Pampati S, Fodeman A, Van Handel M, Zheng L, Ye Z, Yaesoubi R, Salomon JA. (2026). Indirect state-level estimation of sexual minority adolescent populations by sex, age, and race/ethnicity using random forests. PloS one, 21(6)

Murray-Watson RE, Guaracha X, Bilinski A, Yaesoubi R. (2026). Forecasting Local Surges in COVID-19 Hospitalizations through Adaptive Decision Tree Classifiers. Medical decision making : an international journal of the Society for Medical Decision Making

Li J, Murray-Watson RE, St Cyr SB, Grad YH, Warren JL, Yaesoubi R. (2025). Association between city-level sociodemographic and health factors and the prevalence of antimicrobial-resistant gonorrhea in the US, 2000-2019: a spatial-temporal modeling study. Lancet regional health. Americas, (43)

Yaesoubi R. (2025). Author Reply. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Neves MR, Franke M, Mitnick C, Ciobanu N, Crudu V, Furin J, Cohen T, Yaesoubi R. (2025). Using risk prediction models to inform personalized, cost-effective treatment recommendations. medRxiv : the preprint server for health sciences

Hassan S, Yaesoubi R, Magnus OBH, Kanthali M, Purohit MR, Mustafa T. (2025). Factors associated with the delay in diagnosis of extrapulmonary tuberculosis at the patient and health system level: A study from a rural setting in India. PloS one, 20(1)

Li J, Murray-Watson RE, St Cyr SB, Grad YH, Warren JL, Yaesoubi R. (2025). Correction to "Association between city-level sociodemographic and health factors and the prevalence of antimicrobial-resistant gonorrhea in the US, 2000-2019: a spatial-temporal modeling study" The Lancet Regional Health-Americas 2025; 43, 101006]. Lancet regional health. Americas, (45)

Tu LH, Melnick E, Venkatesh AK, Sheth KN, Navaratnam D, Yaesoubi R, Forman HP, Mahajan A. (2024). Reply to "Considering Health Systems Worldwide: Point of View From a Middle-Income Country". AJR. American journal of roentgenology

Yaesoubi R, Kunst N. (2024). Net Monetary Benefit Lines Augmented with Value-of-Information Measures to Present the Results of Economic Evaluations under Uncertainty. Medical decision making : an international journal of the Society for Medical Decision Making

Yin X, Li Y, Rönn MM, Li S, Yuan Y, Gift TL, Hsu K, Salomon JA, Grad YH, Yaesoubi R. (2024). Assessing thresholds of resistance prevalence at which empiric treatment of gonorrhea should change among men who have sex with men in the US: A cost-effectiveness analysis. PLoS medicine, 21(7)

Yaesoubi R. (2024). How many Monte Carlo samples are needed for probabilistic cost-effectiveness analyses?. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Hassan S, Purohit MR, Kanthali M, Yaesoubi R, Jain S, Mustafa T. (2024). Health-related quality of life among extrapulmonary tuberculosis patients and inequalities by disease manifestations: a longitudinal study analysing the impact of TB treatment. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

James LP, Klaassen F, Sweeney S, Furin J, Franke MF, Yaesoubi R, Chesov D, Ciobanu N, Codreanu A, Crudu V, Cohen T, Menzies NA. (2024). Impact and cost-effectiveness of the 6-month BPaLM regimen for rifampicin-resistant tuberculosis in Moldova: A mathematical modeling analysis. PLoS medicine, 21(5)

Murray-Watson RE, Grad YH, St Cyr SB, Yaesoubi R. (2024). Personalizing the empiric treatment of gonorrhea using machine learning models. PLOS digital health, 3(8)

You S, Yaesoubi R, Lee K, Li Y, Eppink ST, Hsu KK, Chesson HW, Gift TL, Berruti AA, Salomon JA, Rönn MM. (2023). Lifetime quality-adjusted life years lost due to genital herpes acquired in the United States in 2018: a mathematical modeling study. Lancet regional health. Americas, (19)

Pryor S, Savoye M, Nowicka P, Price G, Sharifi M, Yaesoubi R. (2023). Cost-Effectiveness and Long-Term Savings of the Bright Bodies Intervention for Childhood Obesity. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 26(8)

Yaesoubi R, You S, Xi Q, Menzies NA, Tuite A, Grad YH, Salomon JA. (2023). Generating simple classification rules to predict local surges in COVID-19 hospitalizations. Health care management science, 26(2)

Yaesoubi R, Xi Q, Hsu K, Gift TL, St Cyr SB, Rönn MM, Salomon JA, Grad YH. (2023). The Impact of Rapid Drug Susceptibility Tests on Gonorrhea Burden and Lifespan of Antibiotic Treatments: A Modeling Study Among Men Who Have Sex With Men in the United States. American journal of epidemiology

Li Y, You S, Lee K, Yaesoubi R, Hsu K, Gift TL, Chesson HW, Berruti AA, Salomon JA, Rönn MM. (2023). The Estimated Lifetime Quality-Adjusted Life-Years Lost Due to Chlamydia, Gonorrhea, and Trichomoniasis in the United States in 2018. The Journal of infectious diseases, 227(8)

Reichert E, Yaesoubi R, Rönn MM, Gift TL, Salomon JA, Grad YH. (2023). Resistance-minimising strategies for introducing a novel antibiotic for gonorrhoea treatment: a mathematical modelling study. The Lancet. Microbe

Tu LH, Melnick E, Venkatesh AK, Sheth KN, Navaratnam D, Yaesoubi R, Forman HP, Mahajan A. (2023). Cost-Effectiveness of CT, CTA, MRI, and Specialized MRI for Evaluation of Patients Presenting to the Emergency Department With Dizziness. AJR. American journal of roentgenology

Tu LH, Malhotra A, Venkatesh AK, Taylor RA, Sheth KN, Yaesoubi R, Forman HP, Sureshanand S, Navaratnam D. (2023). Clinical criteria to exclude acute vascular pathology on CT angiogram in patients with dizziness. PloS one, 18(3)

Phillips MT, Antillon M, Bilcke J, Bar-Zeev N, Limani F, Debellut F, Pecenka C, Neuzil KM, Gordon MA, Thindwa D, Paltiel AD, Yaesoubi R, Pitzer VE. (2023). Cost-effectiveness analysis of typhoid conjugate vaccines in an outbreak setting: a modeling study. BMC infectious diseases, 23(1)

Tu LH, Navaratnam D, Melnick E, Forman HP, Venkatesh AK, Malhotra A, Yaesoubi R, Sureshanand S, Sheth KN, Mahajan A. (2023). CT With CTA Versus MRI in Patients Presenting to the Emergency Department With Dizziness: Analysis Using Propensity Score Matching. AJR. American journal of roentgenology

You S, Chitwood MH, Gunasekera KS, Crudu V, Codreanu A, Ciobanu N, Furin J, Cohen T, Warren JL, Yaesoubi R. (2022). Predicting resistance to fluoroquinolones among patients with rifampicin-resistant tuberculosis using machine learning methods. PLOS digital health, 1(6)

Tu LH, Malhotra A, Sheth KN, Yaesoubi R, Forman HP, Venkatesh AK. (2022). Yield of Head Computed Tomography Examinations for Common Psychiatric Presentations and Implications for Medical Clearance From a 6-Year Analysis of Acute Hospital Visits. JAMA internal medicine

de Villiers AK, Dye C, Yaesoubi R, Cohen T, Marx FM. (2022). Spatially targeted digital chest radiography to reduce tuberculosis in high-burden settings: A study of adaptive decision making. Epidemics, (38)

Yaesoubi R, Cohen T, Hsu K, Gift TL, St Cyr SB, Salomon JA, Grad YH. (2022). Evaluating spatially adaptive guidelines for the treatment of gonorrhea to reduce the incidence of gonococcal infection and increase the effective lifespan of antibiotics. PLoS computational biology, 18(2)

Lee K, You S, Li Y, Chesson H, Gift TL, Berruti AA, Hsu K, Yaesoubi R, Salomon JA, Rönn M. (2022). Estimation of the Lifetime Quality-Adjusted Life Years (QALYs) Lost Due to Syphilis acquired in the United States in 2018. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Tu LH, Malhotra A, Venkatesh AK, Taylor RA, Sheth KN, Forman HP, Yaesoubi R. (2021). Head and Neck CTA Utilization: Analysis of Ordering Frequency and Nonroutine Results Communication, With Focus on the Fifty Most Common Emergency Department Clinical Presentations. AJR. American journal of roentgenology

Yaesoubi R, Havumaki J, Chitwood MH, Menzies NA, Gonsalves G, Salomon JA, Paltiel AD, Cohen T. (2021). Adaptive Policies to Balance Health Benefits and Economic Costs of Physical Distancing Interventions during the COVID-19 Pandemic. Medical decision making : an international journal of the Society for Medical Decision Making

Yaesoubi R, Mahin M, Martin G, Paltiel AD, Sharifi M. (2021). Reducing the Prevalence of Alcohol-Exposed Pregnancies in the United States: A Simulation Modeling Study. Medical decision making : an international journal of the Society for Medical Decision Making

Yaesoubi R, You S, Xi Q, Menzies NA, Tuite A, Grad YH, Salomon JA. (2021). Simple decision rules to predict local surges in COVID-19 hospitalizations during the winter and spring of 2022. medRxiv : the preprint server for health sciences

Tu LH, Venkatesh AK, Malhotra A, Taylor RA, Sheth KN, Forman HP, Yaesoubi R. (2021). Scenarios to improve CT head utilization in the emergency department delineated by critical results reporting. Emergency radiology

Yaesoubi R, Havumaki J, Chitwood MH, Menzies NA, Gonsalves G, Salomon J, Paltiel AD, Cohen T. (2020). Adaptive policies for use of physical distancing interventions during the COVID-19 pandemic. medRxiv : the preprint server for health sciences

Yaesoubi R, Cohen T, Hsu K, Gift TL, Chesson H, Salomon JA, Grad YH. (2020). Adaptive guidelines for the treatment of gonorrhea to increase the effective life span of antibiotics among men who have sex with men in the United States: A mathematical modeling study. PLoS medicine, 17(4)

Marx FM, Cohen T, Menzies NA, Salomon JA, Theron G, Yaesoubi R. (2020). Cost-effectiveness of post-treatment follow-up examinations and secondary prevention of tuberculosis in a high-incidence setting: a model-based analysis. The Lancet. Global health, 8(9)

Hsieh YL, Jahn A, Menzies NA, Yaesoubi R, Salomon JA, Girma B, Gunde L, Eaton JW, Auld A, Odo M, Kiyiika CN, Kalua T, Chiwandira B, Mpunga JU, Mbendra K, Corbett L, Hosseinipour MC, Cohen T, Kunkel A. (2020). Evaluation of 6-Month Versus Continuous Isoniazid Preventive Therapy for Mycobacterium tuberculosis in Adults Living With HIV/AIDS in Malawi. Journal of acquired immune deficiency syndromes (1999), 85(5)

Leuba SI, Yaesoubi R, Antillon M, Cohen T, Zimmer C. (2020). Tracking and predicting U.S. influenza activity with a real-time surveillance network. PLoS computational biology, 16(11)

Arifin SMN, Zimmer C, Trotter C, Colombini A, Sidikou F, LaForce FM, Cohen T, Yaesoubi R. (2019). Cost-Effectiveness of Alternative Uses of Polyvalent Meningococcal Vaccines in Niger: An Agent-Based Transmission Modeling Study. Medical decision making : an international journal of the Society for Medical Decision Making, 39(5)

Yap A, Cheung M, Muzira A, Healy J, Kakembo N, Kisa P, Cunningham D, Youngson G, Sekabira J, Yaesoubi R, Ozgediz D. (2019). Best Buy in Public Health or Luxury Expense?: The Cost-effectiveness of a Pediatric Operating Room in Uganda From the Societal Perspective. Annals of surgery

Kaufhold S, Yaesoubi R, Pitzer VE. (2019). Predicting the Impact of Typhoid Conjugate Vaccines on Antimicrobial Resistance. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 68(Supplement_2)

Yap A, Muzira A, Cheung M, Healy J, Kakembo N, Kisa P, Cunningham D, Youngson G, Sekabira J, Yaesoubi R, Ozgediz D. (2018). A Cost-Effectiveness Analysis of a Pediatric Operating Room in Uganda. Surgery, 164(5)

Marx FM, Yaesoubi R, Menzies NA, Salomon JA, Bilinski A, Beyers N, Cohen T. (2018). Tuberculosis control interventions targeted to previously treated people in a high-incidence setting: a modelling study. The Lancet. Global health, 6(4)

Menzies NA, Cohen T, Hill AN, Yaesoubi R, Galer K, Wolf E, Marks SM, Salomon JA. (2018). Prospects for Tuberculosis Elimination in the United States: Results of a Transmission Dynamic Model. American journal of epidemiology, 187(9)

Zimmer C, Leuba SI, Cohen T, Yaesoubi R. (2019). Accurate quantification of uncertainty in epidemic parameter estimates and predictions using stochastic compartmental models. Statistical methods in medical research, 28(12)

Menzies NA, Wolf E, Connors D, Bellerose M, Sbarra AN, Cohen T, Hill AN, Yaesoubi R, Galer K, White PJ, Abubakar I, Salomon JA. (2018). Progression from latent infection to active disease in dynamic tuberculosis transmission models: a systematic review of the validity of modelling assumptions. The Lancet. Infectious diseases, 18(8)

Zimmer C, Leuba SI, Yaesoubi R, Cohen T. (2018). Use of daily Internet search query data improves real-time projections of influenza epidemics. Journal of the Royal Society, Interface, 15(147)

Yaesoubi R, Trotter C, Colijn C, Yaesoubi M, Colombini A, Resch S, Kristiansen PA, LaForce FM, Cohen T. (2017). The cost-effectiveness of alternative vaccination strategies for polyvalent meningococcal vaccines in Burkina Faso: A transmission dynamic modeling study. PLoS medicine, 15(1)

Zimmer C, Yaesoubi R, Cohen T. (2016). A Likelihood Approach for Real-Time Calibration of Stochastic Compartmental Epidemic Models. PLoS computational biology, 13(1)

Yaesoubi R, Cohen T. (2016). Identifying cost-effective dynamic policies to control epidemics. Statistics in medicine, 35(28)

Yaesoubi R, Cohen T. (2013). Identifying dynamic tuberculosis case-finding policies for HIV/TB coepidemics. Proceedings of the National Academy of Sciences of the United States of America, 110(23)

Yaesoubi R, Roberts SD. (2011). Payment contracts in a preventive health care system: a perspective from operations management. Journal of health economics, 30(6)

Yaesoubi R, Cohen T. (2011). Dynamic health policies for controlling the spread of emerging infections: influenza as an example. PLoS One, 6(9)

Yaesoubi R, Cohen T. (2011). Generalized Markov Models of Infectious Disease Spread: A Novel Framework for Developing Dynamic Health Policies. European journal of operational research, 215(3)

Joseph P Bigus, Murray Campbell, Boaz Carmeli, Melissa Cefkin, Henry Chang, C-H Chen-Ritzo, William F Cody, Shahram Ebadollahi, A Evfimievski, Ariel Farkash, Susanne Glissmann, David Gotz, TWA Grandison, Daniel Gruhl, Peter J Haas, Mark JH Hsiao, P-YS Hsueh, Jianying Hu, Joseph M Jasinski, James H Kaufman, Cheryl A Kieliszewski, Martin S Kohn, Sarah E Knoop, Paul P Maglio, Ronald L Mak, Haim Nelken, Chalapathy Neti, Hani Neuvirth, Yue Pan, Yardena Peres, Sreeram Ramakrishnan, Reza Yaesoubi. (2011). Information technology for healthcare transformation. IBM Journal of Research and Development, 55(5)

Yaesoubi R, Roberts SD. (2010). A game-theoretic framework for estimating a health purchaser's willingness-to-pay for health and for expansion. Health care management science, 13(4)

Reza Yaesoubi, Stephen D Roberts, Robert W Klein. (2010). A modification of Cheng's method: An alternative Factor Screening method for stochastic simulation models. Proceedings of the 2010 Winter Simulation Conference

R. Yaesoubi and S. D. Roberts. (2008). How much is a health insurer willing to pay for Colorectal Cancer screening tests?. 2008 Winter Simulation Conference

RW Klein, R Yaesoubi, SD Roberts. (2007). PCV64 FACTOR SCREENING FOR PARSIMONY OF VARIABLES IN PHARMACOECONOMIC MODELS. Value in Health, 10(3)

Reza Yaesoubi, Stephen D Roberts. (2007). Important factors in screening for colorectal cancer. 2007 Winter Simulation Conference

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